# From a Molecule to a Drug: Chemical Features Enhancing Pharmacological Potential II

**Authors:** Giovanni Ribaudo, Laura Orian

PMC · DOI: 10.3390/molecules31040627 · Molecules · 2026-02-12

## Full-text entities

- **Genes:** JAK3 (Janus kinase 3) [NCBI Gene 3718] {aka JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK}, BTK (Bruton tyrosine kinase) [NCBI Gene 695] {aka AGMX1, AT, ATK, BPK, IGHD3, IMD1}
- **Diseases:** Age-Related Macular Degeneration (MESH:D008268), Melanoma (MESH:D008545), injury to (MESH:D014947), toxicity (MESH:D064420)
- **Chemicals:** 2-(4-Isobutylphenyl)propanoic acid (MESH:D007052), 1,2,4-Triazole Coupled Acetamide (-), 10-Hydroxydecanoic Acid (MESH:C000621793)
- **Species:** Lomentospora prolificans (species) [taxon 41688], Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12942735/full.md

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Source: https://tomesphere.com/paper/PMC12942735