# The Cardiovascular Disease Continuum: From Cardiovascular Risk Factors to Heart Failure

**Authors:** Mariana Floria, Anca Victorita Trifan, Daniela Maria Tanase

PMC · DOI: 10.3390/life16020308 · Life · 2026-02-11

## Full-text entities

- **Genes:** PCSK9 (proprotein convertase subtilisin/kexin type 9) [NCBI Gene 255738] {aka FH3, FHCL3, HCHOLA3, LDLCQ1, NARC-1, NARC1}, DCN (decorin) [NCBI Gene 1634] {aka CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B}, MUC16 (mucin 16, cell surface associated) [NCBI Gene 94025] {aka CA125}, RET (ret proto-oncogene) [NCBI Gene 5979] {aka CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1}, mucin [NCBI Gene 100508689]
- **Diseases:** myocardial systolic impairment (MESH:D000092244), hypertriglyceridemia (MESH:D015228), cardiovascular abnormalities (MESH:D018376), atopic dermatitis (MESH:D003876), of the coronary microcirculation (MESH:D003323), alkaptonuria (MESH:D000474), thromboembolic (MESH:D013923), allergic (MESH:D004342), cardiac disease (MESH:D006331), ovarian cancer (MESH:D010051), coronary artery disease (MESH:D003324), peripheral arterial disease (MESH:D058729), sleep apnea-hypopnea syndrome (MESH:D020181), HF (MESH:D006333), Hypercholesterolemia (MESH:D006937), toxic (MESH:D064420), pulmonary artery dilation (MESH:D000071079), cerebrovascular disease (MESH:D002561), CVD (MESH:D002318), mineral and bone disorder (MESH:D012080), RV dysfunction (MESH:D018497), ischemic stroke (MESH:D002544), AF (MESH:D001281), myocardial ischemia (MESH:D017202), death (MESH:D003643), hypertension (MESH:D006973), Atherosclerosis (MESH:D050197), inherited disorder of tyrosine metabolism (MESH:D020739), collapse (MESH:D001261), Aortic stiffness (MESH:C566100), hypoxia (MESH:D000860), Chronic obstructive pulmonary disease (MESH:D029424), cardiomyopathy (MESH:D009202), stroke (MESH:D020521), left ventricular systolic impairment (MESH:D018487), Aortic stenosis (MESH:D001024), arrhythmias (MESH:D001145), angina (MESH:D000787), Ventricular Dysfunction (MESH:D018754), asthma (MESH:D001249), chronic kidney disease (MESH:D051436), dyspnea (MESH:D004417), inspiratory collapse of the inferior vena cava (MESH:C563013), cancers (MESH:D009369), diabetes (MESH:D003920), endothelial dysfunction (MESH:D014652), valvular degeneration and dysfunction (MESH:D006349), dyslipidemia (MESH:D050171), myocardial remodeling (MESH:D064752), Coronary microvascular dysfunction (MESH:D003327), Chronic coronary syndrome (MESH:D054058), Allergic inflammation (MESH:D007249), injury to (MESH:D014947)
- **Chemicals:** lipid (MESH:D008055), triglyceride (MESH:D014280), ezetimibe (MESH:D000069438)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

24 references — full list in the complete paper: https://tomesphere.com/paper/PMC12942550/full.md

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Source: https://tomesphere.com/paper/PMC12942550