# Risk Factors of Requiring Tracheostomy in COVID-19 Patients: A Retrospective Analysis of Intubated Patients

**Authors:** Annika Bharwani, Laith A. Ayasa, Camilo A. Avendano, Raymond C. Parrish, Juan C. Lara, Juan C. Cedeno, Kai Swenson, Jason Beattie, Adnan Majid, Mihir S. Parikh

PMC · DOI: 10.3390/jcm15041342 · Journal of Clinical Medicine · 2026-02-08

## TL;DR

This study identifies risk factors for needing a tracheostomy in COVID-19 patients, including age and certain health indicators.

## Contribution

The study provides new insights into early risk factors for tracheostomy in intubated COVID-19 patients.

## Key findings

- Age, P/F ratio, creatinine level, and history of arrhythmia are significantly associated with tracheostomy need.
- The findings suggest potential for early identification of patients at risk for prolonged ventilation.
- Further validation with a larger sample is recommended to confirm these risk factors.

## Abstract

Background: Prolonged mechanical ventilation and tracheostomy in patients with COVID-19 is associated with longer hospital stays. Guidance on which patients are at risk for tracheostomy due to the progression of COVID-19 is limited. Objectives: This study aimed to identify risk factors associated with the need for tracheostomy in patients intubated for COVID-19 between 1 March and 31 December 2020. Methods: The methodology for this study involved a single-center retrospective analysis of 120 patients who were intubated due to COVID-19 infection between 1 March 2020 and 31 December 2020. A comparison of variables was performed using the Wilcoxon test, Chi-squared test, and Fisher’s exact test alongside univariate analysis. Results: Several risk factors were found to be significantly associated with the need for tracheostomy, including age, P/F ratio, creatinine level, and history of arrhythmia. Conclusions: Initial exploration indicates the presence of certain factors that can help us understand future need for tracheostomy earlier in the patient’s clinical course. Further analysis should be performed with a larger sample size to validate these findings and increase the generalizability of the present study.

## Linked entities

- **Diseases:** COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** arrhythmia (MESH:D001145), hypoxemic respiratory failure (MESH:D012131), pneumonia (MESH:D011014), ARDS (MESH:D012128), hypoxemia (MESH:D000860), SARS (MESH:D045169), critically ill (MESH:D016638), alveolar injury (MESH:D014947), Death (MESH:D003643), COVID (MESH:D000086382), atrial fibrillation (MESH:D001281), Immune-compromised (MESH:D007154), infection (MESH:D007239)
- **Chemicals:** Creatinine (MESH:D003404), bilirubin (MESH:D001663)
- **Species:** Severe acute respiratory syndrome coronavirus 2 (no rank) [taxon 2697049], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

25 references — full list in the complete paper: https://tomesphere.com/paper/PMC12942540/full.md

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Source: https://tomesphere.com/paper/PMC12942540