# Platform-Dependent Differences in Beam Characteristics and Low-Dose Exposure: A Comparative Study of Elekta™ Synergy and Varian TrueBeam™ Linear Accelerators Using SunSCAN™ 3D Phantom and Octavius® 4D QA

**Authors:** Marian-Răzvan Bălan, Anda Elena Crișan, Eugen Osiac, Cristiana-Iulia Dumitrescu, Suzana Măceș, Mihai Popescu, Luana Corina Lascu, Maria Mihai, Sanda-Amelia Drăcea, Oana Ciobănescu, Mădălin-Cristian Moraru, Daniela Dumitrescu

PMC · DOI: 10.3390/jcm15041619 · 2026-02-20

## TL;DR

This study compares dosimetric performance between Elekta Synergy and Varian TrueBeam linear accelerators, finding small but clinically relevant platform-dependent differences in low-dose exposure and beam characteristics.

## Contribution

The study identifies platform-specific dosimetric variations in clinically commissioned treatment plans using real QA systems and patient cases.

## Key findings

- Platform-dependent differences in penumbra and out-of-field dose were linked to linac head design and collimation.
- Breast and head and neck plans showed greater variability between platforms compared to prostate plans.
- All plans met clinical acceptance criteria, but gamma evaluation revealed minor systematic deviations.

## Abstract

Background/Objectives: Inter-platform variability in beam characteristics and low-dose exposure may arise from differences in linear accelerator head design, multileaf collimator geometry, and dose calculation algorithms. This study aimed to evaluate system-level dosimetric differences between two widely used linear accelerator platforms under clinically commissioned conditions. Methods: A comparative dosimetric analysis was performed between Elekta Synergy and Varian TrueBeam linear accelerators. Beam data were acquired using a SunSCAN™ 3D water phantom, and patient-specific quality assurance was conducted with the Octavius® 4D system. Treatment plans were generated for left-sided breast, prostate, and head and neck cases using clinically commissioned treatment planning systems. Beam flatness, symmetry, penumbra width, low-dose exposure, conformity, homogeneity, and organ-at-risk dose metrics were evaluated. Results: Platform-dependent differences were observed in penumbra behavior and out-of-field dose, primarily attributable to intrinsic linac head design and collimation characteristics. These differences propagated into clinical plans, with greater variability observed for breast and head and neck cases, while prostate plans showed higher consistency between platforms. Algorithm-dependent trends were noted for conformity and homogeneity indices; however, all plans met institutional clinical acceptance criteria during quality assurance. Stricter gamma evaluation criteria revealed systematic but limited inter-platform deviations. Conclusions: Elekta Synergy and Varian TrueBeam demonstrated clinically acceptable dosimetric performance, with modest platform-dependent differences. While target coverage and overall plan quality were comparable, these variations were primarily observed in peripheral dose regions and may be relevant for platform-specific planning optimization and quality assurance. This supports the importance of comprehensive commissioning and QA procedures in both mixed- and single-platform clinical settings, particularly for highly modulated techniques.

## Linked entities

- **Diseases:** breast cancer (MONDO:0004989)

## Full-text entities

- **Diseases:** breast cancer (MESH:D001943), H&amp;N (MESH:D000848), HI (MESH:C566784), toxicity (MESH:D064420), prostate cancer:95 (MESH:D011471), injury to (MESH:D014947), cancer (MESH:D009369), Head &amp; Neck (MESH:D006258)
- **Chemicals:** Elekta (-), water (MESH:D014867)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12942439/full.md

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Source: https://tomesphere.com/paper/PMC12942439