# Automatic Childhood Pneumonia Diagnosis Based on Multi-Model Feature Fusion Using Chi-Square Feature Selection

**Authors:** Amira Ouerhani, Tareq Hadidi, Hanene Sahli, Halima Mahjoubi

PMC · DOI: 10.3390/jimaging12020081 · 2026-02-14

## TL;DR

This paper introduces a new method for diagnosing childhood pneumonia using combined deep learning models and feature selection, achieving high accuracy.

## Contribution

A novel pneumonia detection system using multi-model feature fusion and Chi-Square feature selection for improved accuracy and efficiency.

## Key findings

- The proposed system achieved 97.59% accuracy in diagnosing childhood pneumonia.
- It outperformed previous methods with high Recall (98.33%) and F1-score (98.19%).
- The method ensures computational efficiency while maintaining high diagnostic performance.

## Abstract

Pneumonia is one of the main reasons for child mortality, with chest radiography (CXR) being essential for its diagnosis. However, the low radiation exposure in pediatric analysis complicates the accurate detection of pneumonia, making traditional examination ineffective. Progress in medical imaging with convolutional neural networks (CNN) has considerably improved performance, gaining widespread recognition for its effectiveness. This paper proposes an accurate pneumonia detection method based on different deep CNN architectures that combine optimal feature fusion. Enhanced VGG-19, ResNet-50, and MobileNet-V2 are trained on the most widely used pneumonia dataset, applying appropriate transfer learning and fine-tuning strategies. To create an effective feature input, the Chi-Square technique removes inappropriate features from every enhanced CNN. The resulting subsets are subsequently fused horizontally, to generate more diverse and robust feature representation for binary classification. By combining 1000 best features from VGG-19 and MobileNet-V2 models, the suggested approach records the best accuracy (97.59%), Recall (98.33%), and F1-score (98.19%) on the test set based on the supervised support vector machines (SVM) classifier. The achieved results demonstrated that our approach provides a significant enhancement in performance compared to previous studies using various ensemble fusion techniques while ensuring computational efficiency. We project this fused-feature system to significantly aid timely detection of childhood pneumonia, especially within constrained healthcare systems.

## Linked entities

- **Diseases:** pneumonia (MONDO:0005249)

## Full-text entities

- **Genes:** PGR (progesterone receptor) [NCBI Gene 5241] {aka NR3C3, PR}
- **Diseases:** airway obstruction (MESH:D000402), TL (MESH:D007859), Chest Disease (MESH:D002637), Pneumonia (MESH:D011014), cavitary lesion (MESH:C566924), DL (MESH:C537113), lung cancer (MESH:D008175), breathing difficulties (MESH:D004417), lung disease (MESH:D008171), respiratory illness (MESH:D012140), inflammation (MESH:D007249), injury to (MESH:D014947), infected lungs (MESH:D012141), TB (MESH:D014376), bacterial (MESH:D001424), chest (MESH:D013898), fungal pneumonia (MESH:D008172), infected (MESH:D007239), COVID-19 (MESH:D000086382), post (MESH:D000094025), death (MESH:D003643), upper lobe collapse (MESH:D001261)
- **Chemicals:** TP (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

13 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12942337/full.md

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Source: https://tomesphere.com/paper/PMC12942337