Non-Operative, Micro- and Minimally Invasive Methods for Caries Treatment—A Narrative Review
Veselina Todorova

TL;DR
This paper reviews non-surgical and minimally invasive dental treatments for caries, focusing on preserving natural tooth structure and using advanced techniques for better patient outcomes.
Contribution
The paper provides a comprehensive overview of current non-operative and minimally invasive caries treatment methods, emphasizing biological preservation and technological advancements.
Findings
Fluoride therapy and CPP-ACP are effective for remineralization and early caries management.
Laser photoablation with erbium lasers allows precise cavity preparation with less thermal and mechanical stress.
Minimally invasive techniques improve patient comfort and reduce the need for anesthesia while preserving tooth vitality.
Abstract
The management of dental caries has evolved from the traditional mechanical approach of “extension for prevention” to a biologically oriented philosophy centered on preserving natural tooth structures. Minimally invasive dentistry (MID) emphasizes early detection, risk assessment, prevention, and conservative intervention based on the lesion’s activity and depth. This review outlines current evidence on non-operative, micro-invasive, and minimally invasive strategies, including fluoride therapy, remineralizing agents such as casein phosphopeptide–amorphous calcium phosphate (CPP-ACP), self-assembling peptides that promote biomimetic enamel repair, sealants, and resin infiltration. Minimally invasive operative methods employ advanced technologies for selective tissue removal—chemomechanical systems (Carisolv, Papacarie, Brix3000), sono-and airabrasion, and new-generation polymeric and…
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsLaser Applications in Dentistry and Medicine · Dental Erosion and Treatment · Dental Health and Care Utilization
