# Cystic Fibrosis: A Disease with a New Face

**Authors:** Janice Wang, Patricia A. Walker

PMC · DOI: 10.3390/life16020228 · 2026-01-30

## Full-text entities

- **Genes:** CALCA (calcitonin related polypeptide alpha) [NCBI Gene 796] {aka CALC1, CGRP, CGRP-I, CGRP-alpha, CGRP1, CT}, CFTR (CF transmembrane conductance regulator) [NCBI Gene 1080] {aka ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR}
- **Diseases:** genetic disease (MESH:D030342), organ failure (MESH:D009102), lung disease (MESH:D008171), malignancies (MESH:D009369), CF (MESH:D003550), injury to (MESH:D014947), liver disease (MESH:D008107), inflammation (MESH:D007249), oncologic (MESH:D000072716), disordered eating behaviors (MESH:D001068), airway infection (MESH:D007239), bone disease (MESH:D001847), malnutrition (MESH:D044342), bronchiectasis (MESH:D001987)
- **Chemicals:** tezacaftor (MESH:C000625213), elexacaftor (MESH:C000629074), ivacaftor (MESH:C545203), ETI (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Mutations:** F508del, Ile148Thr, Ile1023_Val1024del

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Source: https://tomesphere.com/paper/PMC12941897