# Comparative Effects of Weighted Vest and Whole-Body Vibration Training on Bone and Muscle Health in Osteopenia

**Authors:** Jidapa Tantanasest, Apiwan Manimmanakorn, Orathai Tunkamnerdthai, Chiraphorn Khaengkhan, Peeraporn Nithisup, Suphawijak Youdprang, Nuttaset Manimmanakorn, Michael John Hamlin

PMC · DOI: 10.3390/life16020229 · 2026-02-01

## TL;DR

Wearing a weighted vest during exercise improved bone and muscle health more than whole-body vibration or regular exercise in older women with osteopenia.

## Contribution

Demonstrates that weighted vest training provides greater benefits than whole-body vibration or conventional exercise for bone and muscle health in older women.

## Key findings

- Weighted vest training increased T-score, leg bone mineral density, and leg lean mass more than control and WBV groups.
- Whole-body vibration improved total lean mass and skeletal muscle index compared to control.
- Weighted vest training showed greater physical performance improvements in 5TSTS and 6-MWT tests.

## Abstract

Background: The growing elderly population faces health problems like osteoporosis, but novel exercises like weighted vests (WV) and whole-body vibration (WBV) may help prevent bone loss. Methods: Thirty-one women aged 60–79 years with osteopenia or osteoporosis (T-score −2.15 ± 0.9) were randomly assigned to three groups: a control group performed exercise only; a whole-body vibration group performed the exercise on a 40 Hz, 2 mm vibration platform; and a weighted vest group performed the exercise while wearing a weighted vest. T-score, bone mineral density (BMD), muscle mass, and physical performance were assessed before and after 8 weeks. Results: The WV showed a greater T-score increase than the CT and WBV groups (WV: 0.08 ± 0.03; CT: −0.18 ± 0.04; WBV: −0.11 ± 0.16; p = 0.01, 95%CI). Leg BMD increased in the WV group (1.75 ± 0.13 to 1.79 ± 0.16 g/cm2; p = 0.02). Leg lean mass also increased in the WV (1.28 ± 0.91 kg) compared to WBV (0.17 ± 0.14 kg) and CT (0.06 ± 0.79 kg, p = 0.01, 95%CI). The WV group showed greater physical performance improvements (5TSTS and 6-MWT). The WBV group showed improved total lean mass compared to the CT group (WBV: 0.32 ± 0.17; CT = −1.20 ± 1.86, p = 0.006, 95%CI). Conclusions: WV exercise improved bone density, leg lean mass, and physical performance in older women. WBV exercise increased total lean mass and skeletal muscle index while reducing fat mass. WV exercise provides an additive effect beyond exercise alone or WBV.

## Linked entities

- **Diseases:** osteoporosis (MONDO:0005298)

## Full-text entities

- **Genes:** SOST (sclerostin) [NCBI Gene 50964] {aka CDD, DAND6, SOST1, VBCH}
- **Diseases:** decline in muscle mass (MESH:C536030), Loss of bone mineral density (MESH:D001851), respiratory disorder (MESH:D012131), falls (MESH:C537863), bone resorption (MESH:D001862), COPD (MESH:D029424), hyperthyroidism (MESH:D006980), vitamin D deficiency (MESH:D014808), stroke (MESH:D020521), anxiety (MESH:D001007), Chronic kidney disease (MESH:D051436), asthma (MESH:D001249), sarcopenia (MESH:D055948), muscle atrophy (MESH:D009133), injuries (MESH:D014947), fractures (MESH:D050723), unstable angina (MESH:D000789), musculoskeletal health (MESH:D009140), depression (MESH:D003866), heart failure (MESH:D006333), reduced muscle strength and mass (MESH:D009135), cardiovascular diseases (MESH:D002318), acute myocardial infarction (MESH:D009203), Endocrine disorders (MESH:D004700), hypertrophy (MESH:D006984), Bone loss (MESH:D001847), Osteoporosis (MESH:D010024), hypothyroidism (MESH:D007037), Hypertension (MESH:D006973), muscle, tendon, and ligament injuries (MESH:D013708), nerve damage (MESH:D000080902)
- **Chemicals:** oxygen (MESH:D010100), alcohol (MESH:D000438), bisphosphonates (MESH:D004164), denosumab (MESH:D000069448)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12941892/full.md

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Source: https://tomesphere.com/paper/PMC12941892