# Reply to Wostyn, P.; Nedergaard, M. Ocular Glymphatic Dysfunction as a Potential Link Between Obstructive Sleep Apnea and Retinal Structural Changes. Comment on “Pusic Sesar et al. Multimodal Assessment of Ocular Parameters in Patients with Severe Obstructive Sleep Apnea with Emphasis on Retinal Structural Changes. Life 2025, 15, 1307”

**Authors:** Anita Pusic Sesar, Anja Cehajic, Antonela Geber, Mia Zoric Geber, Ivan Cavar, Antonio Sesar

PMC · DOI: 10.3390/life16020215 · 2026-01-28

## Full-text entities

- **Genes:** APP (amyloid beta precursor protein) [NCBI Gene 351] {aka AAA, ABETA, ABPP, AD1, APPI, CTFgamma}
- **Diseases:** Ocular Glymphatic Dysfunction (MESH:D005128), sleep apnea syndrome (MESH:D012891), OSA (MESH:D020181), glaucoma (MESH:D005901), retinal neurodegeneration (MESH:D012164), glaucomatous changes (MESH:D009402), insomnia (MESH:D007319), injury to (MESH:D014947), neurodegeneration (MESH:D019636), normal-tension glaucoma (MESH:D057066), impaired sleep quality (MESH:D012893), glaucomatous damage (MESH:D020263), hypoxia (MESH:D000860), venous congestion (MESH:D006940)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12941844