# Strategies for Enhancing Conventional Glass Ionomer Cement—A Short Review

**Authors:** Ye Zhang, Jingwei He

PMC · DOI: 10.3390/ma19040653 · 2026-02-08

## TL;DR

This review explores ways to improve glass ionomer cement for dental use by enhancing its strength and durability.

## Contribution

The paper summarizes strategies for enhancing GIC through powder and liquid component modifications.

## Key findings

- Adding reinforcing fillers improves compressive, tensile, and flexural strength of GIC.
- Modifying polyacid chemistry can maintain or enhance fluoride release while improving properties.
- Many lab improvements need clinical validation before practical application.

## Abstract

Conventional glass ionomer cement (GIC) is a reaction product formulated from glass powders and polycarboxylic acid aqueous solution. This material has garnered significant attention in restorative dentistry due to its favorable properties, including chemical adhesion to tooth structure, biocompatibility, and sustained fluoride release, coupled with its minimal pulp irritation. However, its low mechanical strength, high brittleness, and susceptibility to cracking limit its use in stress-bearing areas of teeth. To expand the clinical application scope of GIC and develop an “ideal” dental restorative material, enhancing traditional GIC is necessary. This narrative review summarizes the main strategies for enhancing GIC, covering modifications to both the powder and liquid components. The key findings indicate that incorporating reinforcing fillers into the powder or modifying the polyacid chemistry can significantly improve mechanical properties such as compressive, tensile, and flexural strength. Additionally, some modifications help maintain or enhance fluoride release. However, the translation of many laboratory-based improvements to clinical practice requires further validation. In conclusion, while numerous promising enhancement routes exist, future development should focus on synergistic approaches and rigorous clinical evaluation to advance towards high-performance, durable restorative materials.

## Full-text entities

- **Diseases:** Fracture (MESH:D050723), injury to (MESH:D014947), cytotoxicity (MESH:D064420), GIC (MESH:C567350)
- **Chemicals:** Glass Ionomer (MESH:C015897), Ketac-Silver (MESH:D016722), Polymer (MESH:D011108), C (MESH:D002244), graphene oxide (MESH:C000628730), Chitosan (MESH:D048271), phosphate (MESH:D010710), acid (MESH:D000143), stainless-steel (MESH:D013193), MA (MESH:C030272), zinc (MESH:D015032), metal (MESH:D008670), IA (MESH:C005229), Au (MESH:D006046), AA (MESH:C036658), proline (MESH:D011392), 4-pentenoic acid (MESH:C009785), Ag (MESH:D012834), calcium aluminosilicate (MESH:D000077250), CMC (MESH:C514968), copper (MESH:D003300), Sn (MESH:D014001), CaF2 (MESH:D002124), Al2O3 (MESH:D000537), polyacrylic acid (MESH:C006903), NaF (MESH:D012969), fluoride (MESH:D005459), Water (MESH:D014867), lanthanum (MESH:D007811), silane (MESH:D012821), AlF3 (MESH:C032311), ZnO (MESH:D015034), CeO2 (MESH:C030583), HA (MESH:D017886), 3-butenoic acid (MESH:C479121), AlPO4 (MESH:C012714), sodium hypochlorite (MESH:D012973), amino acid (MESH:D000596), carbon nanotubes (MESH:D037742), Ti (MESH:D014025), SiO2 (MESH:D012822), Ketac-Fil (MESH:C040964), aluminosilicate (MESH:C049037), AACA (-), graphene (MESH:D006108), zirconium (MESH:D015040), calcium (MESH:D002118), N-vinylpyrrolidone (MESH:C042670), strontium (MESH:D013324), methacrylate (MESH:D008689), Cellulose (MESH:D002482), a- (MESH:D001151), H+ (MESH:D006859), MgO (MESH:D008277), ZrO2 (MESH:C028541)
- **Species:** Homo sapiens (human, species) [taxon 9606], Eucalyptus (genus) [taxon 3932]
- **Cell lines:** Fuji — Homo sapiens (Human), Monophasic synovial sarcoma, Cancer cell line (CVCL_D880)

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12941825/full.md

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Source: https://tomesphere.com/paper/PMC12941825