# Recent Advances and Perspectives in Terms of the Therapeutic Effects of Natural Products on Human Diseases

**Authors:** Seung Ho Lee

PMC · DOI: 10.3390/life16020245 · 2026-02-02

## Full-text entities

- **Genes:** AIFM1 (apoptosis inducing factor mitochondria associated 1) [NCBI Gene 9131] {aka AIF, AUNX1, CMT2D, CMTX4, COWCK, COXPD6}
- **Diseases:** non-small-cell lung carcinoma (MESH:D002289), hypoxic (MESH:D002534), neurotoxicity (MESH:D020258), Alzheimer's disease (MESH:D000544), cancer (MESH:D009369), neuroinflammation (MESH:D000090862), chronic kidney disease (MESH:D051436), inflammatory (MESH:D007249), neurodegenerative disorders (MESH:D019636), injury to (MESH:D014947), inflammatory skin diseases (MESH:D012871), PD (MESH:D010300), cognitive deficits (MESH:D003072), neuronal damage (MESH:D009410), renal damage (MESH:D007674), gynecological disorders (MESH:D005831), endometrial hyperplasia (MESH:D004714), glutamate excitotoxicity (MESH:C537425), dementia (MESH:D003704), cytotoxicity (MESH:D064420), inflammatory otorhinolaryngological disorders (MESH:D010038)
- **Chemicals:** resveratrol (MESH:D000077185), progesterone (MESH:D011374), carotenoid (MESH:D002338), sodium benzoate (MESH:D020160), ATP (MESH:D000255), 1-methyl-4-phenylpyridinium (MESH:D015655), HGYGT (-)
- **Species:** Ishige (genus) [taxon 233770], Mosla japonica (species) [taxon 2006541], PX clade (clade) [taxon 569578], Rattus norvegicus (brown rat, species) [taxon 10116], Clostridium (genus) [taxon 1485], Homo sapiens (human, species) [taxon 9606], Solanum lycopersicum (tomato, species) [taxon 4081]
- **Cell lines:** A549 — Homo sapiens (Human), Lung adenocarcinoma, Cancer cell line (CVCL_0023), SH-SY5Y — Homo sapiens (Human), Neuroblastoma, Cancer cell line (CVCL_0019)

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Source: https://tomesphere.com/paper/PMC12941679