# Point-of-Care EEG for Non-Convulsive Seizure and Status Epilepticus: Advances, Limitations, and Future Directions

**Authors:** Ana Leticia Fornari Caprara, Jamir Pitton Rissardo, Hana Rababeh, April Pivonka, Priya Shah, Kaitlyn Piotrowski, Matthew George Petruncio, Anusha Keshireddy, Zehra Jaffri, Arthur Gribachov, Ruchika Moturi, Haashim Khurram, Manisha Koneru, Evren Burakgazi-Dalkilic

PMC · DOI: 10.3390/jcm15041643 · 2026-02-22

## TL;DR

Point-of-care EEG is a promising tool for quickly detecting non-convulsive seizures and improving neurological care in emergency settings.

## Contribution

This review highlights recent advances, limitations, and future directions of POC-EEG in detecting seizures and related conditions.

## Key findings

- POC-EEG enables earlier seizure detection and faster treatment decisions in acute neurological care.
- Recent improvements in portability and AI-assisted interpretation have increased accessibility for non-specialists.
- Automated detection algorithms show high accuracy but require further validation for focal or low-burden seizure activity.

## Abstract

Point-of-care electroencephalography (POC-EEG) has emerged as a practical tool for the rapid detection of non-convulsive seizures (NCS) and non-convulsive status epilepticus (NCSE) in acute neurological settings where access to conventional EEG is often delayed. This narrative review synthesizes current evidence on the clinical applications, tech-no-logical evolution, and limitations of POC-EEG systems across adult and pediatric populations. Available data suggest that POC-EEG is associated with earlier seizure identification, more timely antiseizure treatment decisions, and reduced dependence on inter-facility transfers in selected healthcare settings. Beyond seizure detection, POC-EEG has shown potential utility in the assessment of acute encephalopathy due to conditions such as stroke, traumatic brain injury, delirium, and post-cardiac arrest states. Recent advances in device portability and artificial intelligence-assisted interpretation have expanded accessibility, enabling use by non-specialist clinicians; however, reduced spatial resolution, artifact susceptibility, and variable performance in focal or low-burden epileptiform activity remain important limitations. Automated detection algorithms show high accuracy for sustained seizure burden but require cautious interpretation and further prospective validation. Ethical and health-system considerations, including equitable access, diagnostic stewardship, and data governance, are increasingly relevant as adoption grows. Overall, POC-EEG represents a promising adjunct to conventional EEG that may improve early diagnostic workflows in acute neurological care, while definitive impacts on long-term outcomes warrant further study.

## Linked entities

- **Diseases:** stroke (MONDO:0005098), traumatic brain injury (MONDO:0858950), delirium (MONDO:0045057)

## Full-text entities

- **Diseases:** hemorrhagic stroke (MESH:D000083302), Cardiac Arrest (MESH:D006323), TBI (MESH:D000070642), ischemic (MESH:D002545), LOC (MESH:D014474), functional decline (MESH:D060825), Alzheimer's disease (MESH:D000544), muscle (MESH:D019042), skin irritation (MESH:D012871), head injury (MESH:D006259), cerebral dysfunction (MESH:D002547), critically (MESH:D016638), Disease (MESH:D004194), Injury (MESH:D014947), NCSE (MESH:D013226), post-traumatic amnesia (MESH:D004834), ischemia (MESH:D007511), neurologic decline (MESH:D009461), Seizure (MESH:D012640), Stroke (MESH:D020521), disorder of cerebral function (MESH:D003291), Delirium (MESH:D003693), neurological emergencies (MESH:D004630), hypoxic (MESH:D002534), acute encephalopathy (MESH:D000071072), intracranial hemorrhage (MESH:D020300), AI (MESH:C538142), language disturbance (MESH:D007806), aphasia (MESH:D001037), concussion (MESH:D001924), hemiparesis (MESH:D010291), post (MESH:D000094025), ischemic stroke (MESH:D002544), intracerebral hemorrhage (MESH:D002543), brain dysfunction (MESH:D001927), brain injury (MESH:D001930), neurological injury (MESH:D020196), altered consciousness (MESH:D003244), myoclonus (MESH:D009207), death (MESH:D003643), Epilepsy (MESH:D004827), EEG abnormalities (MESH:D000014), activity (OMIM:612348), metabolic encephalopathies (MESH:D001928), sepsis (MESH:D018805), nonconvulsive seizures (MESH:D004829), Coma (MESH:D003128), cognitive impairment (MESH:D003072), axonal injury (MESH:D001480), movement artifacts (MESH:D009069), prolonged seizures (MESH:D008133), HIE (MESH:D020925), cerebral injury (MESH:D000070625), cortical dysfunction (MESH:D054220), traumatic hematomas (MESH:D020202), neuronal injury (MESH:D009410), post-cardiac arrest encephalopathy:21 (MESH:D000080942), IEA (MESH:D014277)
- **Chemicals:** benzodiazepines (MESH:D001569), CerebAir (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12941532/full.md

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Source: https://tomesphere.com/paper/PMC12941532