# Research Progress on the Interaction Mechanism Between Morchella and Mycoparasitic Fungi Causing Diseases and Their Biological Control: A Review

**Authors:** Ruihua Zhao, Jiayi Xie, Pengfei Jin, Xiaolong He

PMC · DOI: 10.3390/jof12020146 · 2026-02-17

## TL;DR

This review discusses the fungal diseases affecting Morchella and their control, focusing on infection mechanisms and biological strategies.

## Contribution

The paper provides a comprehensive review of Morchella fungal diseases and their biological control methods.

## Key findings

- Ten fungal diseases of Morchella have been reported, including white mold and cobweb disease.
- Mycoparasitic fungi infect Morchella through secreted proteins and secondary metabolites.
- Biological control uses antagonistic microorganisms and natural products to manage these diseases.

## Abstract

Morchella is a highly valued edible and medicinal fungus with significant nutritional and economic value. In recent years, with the development of artificial cultivation techniques, the planting area of Morchella has been expanding continuously, while the incidence of fungal diseases has also increased sharply, seriously affecting its yield and quality and further restricting the development of the Morchella industry. To date, ten fungal diseases of Morchella have been reported, mainly including white mold, cobweb disease, pileus rot and fungal rot. The mycoparasitic fungi responsible for these diseases can infect Morchella by secreting proteins and secondary metabolites, while Morchella responds to fungal disease stress through genetic and metabolic regulation. Currently, biological control strategies for Morchella fungal diseases primarily rely on antagonistic microorganisms and natural products. This review summarizes the research progress on major fungal diseases of Morchella, including their causal fungi, pathogenic factors and infection mechanisms, host response mechanisms, and biological control. It also identifies existing research gaps and prospects for future research directions.

## Linked entities

- **Species:** Morchella (taxon 5193)

## Full-text entities

- **Diseases:** Cobweb Disease (MESH:D004194), injury to (MESH:D014947), P. longispora infection (MESH:D016720), Infection (MESH:D007239), white (MESH:D000090122), tumor (MESH:D009369), soil-borne diseases (MESH:D005242), pileus rot (MESH:D005535), fatigue (MESH:D005221), fungal disease (MESH:D009181), necrosis (MESH:D009336), dry bubble disease (MESH:C531816)
- **Chemicals:** D-phenylalanine (-), proline (MESH:D011392), unsaturated fatty acids (MESH:D005231), sugars (MESH:D000073893), 1-Octen-3-ol (MESH:C038844), septocylindrin B (MESH:C519246), ergosterol (MESH:D004875), nitrogen (MESH:D009584), amino acids (MESH:D000596), beta-1,3-glucan (MESH:C033363), o-phenylenediamine (MESH:C034193), ochratoxin A (MESH:C025589), chitin (MESH:D002686), carbon (MESH:D002244), pentose phosphate (MESH:D010428), fatty acid (MESH:D005227), carbohydrate (MESH:D002241), tyrosine (MESH:D014443), sorbic acid (MESH:D013011), phenolic acids (MESH:C017616), nucleotides (MESH:D009711), lipid (MESH:D008055), essential oils (MESH:D009822), fusarubin (MESH:C000625962), melanin (MESH:D008543), alkaloids (MESH:D000470), peptaibols (MESH:D054848), L-glutamic acid (MESH:D018698), trehalose (MESH:D014199), eugenol (MESH:D005054), ROS (MESH:D017382)
- **Species:** Morchella rufobrunnea (blushing morel, species) [taxon 368404], Streptomyces rochei (species) [taxon 1928], Clonostachys rosea (species) [taxon 29856], Agaricus bisporus (common mushroom, species) [taxon 5341], Pseudomonas putida (species) [taxon 303], Purpureocillium lilacinum (species) [taxon 33203], Manihot esculenta (cassava, species) [taxon 3983], Cladobotryum protrusum (species) [taxon 767780], Rhodococcus (genus) [taxon 1661425], Pedobacter sp. (species) [taxon 1411316], Lecanicillium sp. (species) [taxon 1756136], Morchella (true morels, genus) [taxon 5193], Trichoderma atroviride (species) [taxon 63577], Cladobotryum mycophilum (species) [taxon 491253], Aspergillus niger (species) [taxon 5061], Zelopaecilomyces penicillatus (species) [taxon 264952], Fusarium graminearum (species) [taxon 5518], Fusarium nematophilum (species) [taxon 1053271], Pseudomonas chlororaphis (species) [taxon 587753], Homo sapiens (human, species) [taxon 9606], Alternaria alternata (species) [taxon 5599], Hypomyces aurantius (species) [taxon 29852], Fusarium incarnatum (species) [taxon 298378], Fusarium oxysporum (species) [taxon 5507], Penaeus penicillatus (species) [taxon 161924], P. longispora [taxon 228891], Pestalotiopsis trachycarpicola (species) [taxon 1198446], Ovis aries (domestic sheep, species) [taxon 9940], Morchella sextelata (species) [taxon 1174677], Fusarium equiseti (species) [taxon 61235], Cladosporium scabrellum (species) [taxon 887102], Bacillus (genus) [taxon 55087], Zingiber officinale (ginger, species) [taxon 94328], Allium sativum (garlic, species) [taxon 4682], Fungi (kingdom) [taxon 4751], Lecanicillium aphanocladii (species) [taxon 132584]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12941433/full.md

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Source: https://tomesphere.com/paper/PMC12941433