# Special Issue “New Drugs Regulating Cytoskeletons in Human Health and Diseases”

**Authors:** Gilles Breuzard, Maxime Robin, Hervé Kovacic

PMC · DOI: 10.3390/ijms27041911 · International Journal of Molecular Sciences · 2026-02-17

## Full-text entities

- **Genes:** TRPM8 (transient receptor potential cation channel subfamily M member 8) [NCBI Gene 79054] {aka LTRPC6, LTrpC-6, TRPP8, trp-p8}, AKT1 (AKT serine/threonine kinase 1) [NCBI Gene 207] {aka AKT, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA}, TRPV1 (transient receptor potential cation channel subfamily V member 1) [NCBI Gene 7442] {aka VR1}, HDAC9 (histone deacetylase 9) [NCBI Gene 9734] {aka HD7, HD7b, HD9, HDAC, HDAC7B, HDAC9B}, PIK3CB (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta) [NCBI Gene 5291] {aka P110BETA, PI3K, PI3KBETA, PIK3C1}, POTEF (POTE ankyrin domain family member F) [NCBI Gene 728378] {aka A26C1B, POTE2alpha, POTEACTIN}, ADCYAP1 (adenylate cyclase activating polypeptide 1) [NCBI Gene 116] {aka PACAP}, TP53 (tumor protein p53) [NCBI Gene 7157] {aka BCC7, BMFS5, LFS1, P53, TRP53}, HDAC6 (histone deacetylase 6) [NCBI Gene 10013] {aka CPBHM, HD6, JM21, KDAC6, PPP1R90}, MAPT (microtubule associated protein tau) [NCBI Gene 4137] {aka DDPAC, FTD1, FTDP-17, MAPTL, MSTD, MTBT1}
- **Diseases:** mitochondrial (MESH:D028361), Pain (MESH:D010146), metastasis (MESH:D009362), Gliomas (MESH:D005910), injury to (MESH:D014947), Neurodegenerative Diseases (MESH:D019636), numbness (MESH:D006987), Tumour (MESH:D009369), cardiovascular pathologies (MESH:D002318), cardiac disorder (MESH:D006331), peripheral neuropathy (MESH:D010523), Breast Cancer (MESH:D001943), TNBC (MESH:D064726), heart failure (MESH:D006333), PIPNP (MESH:D009437), neuron toxicity (MESH:D009410), Diastolic Heart Disease (MESH:D054144), brain tumors (MESH:D001932), neuropathies (MESH:D009422), GBM (MESH:D005909), mechanical hyperalgesia (MESH:D006930)
- **Chemicals:** 2-aminothiazole (MESH:C004483), pironetin (MESH:C088446), 2-(3',4',5'-trimethoxybenzoyl)benzo[b]furan (-), menthol (MESH:D008610), vinca-alkaloids (MESH:D014748), Paclitaxel (MESH:D017239), taxanes (MESH:D043823), WS-12 (MESH:C533807), flavonoid (MESH:D005419), colchicine (MESH:D003078)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12941164/full.md

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Source: https://tomesphere.com/paper/PMC12941164