# Zinc(II) Coordination Compounds on Acylhydrazones of 2-Tosylaminobenzaldehyde Basis as Promising Luminescent Agents

**Authors:** Elena Braga, Alexey Gusev, Kirill Mamontov, Anatolii Burlov, Valery Vlasenko, Andrey Sidyakin, Marina Ravaeva, Mikhail Kiskin, Wolfgang Linert

PMC · DOI: 10.3390/ijms27041718 · International Journal of Molecular Sciences · 2026-02-10

## TL;DR

This paper reports the synthesis of zinc(II) compounds that show strong luminescence and potential use in OLEDs and bioimaging.

## Contribution

The study introduces new zinc(II) coordination compounds with acylhydrazones as effective luminescent agents.

## Key findings

- The zinc(II) complexes exhibit strong photoluminescence in both solution and solid states.
- The compounds show potential for use in OLED devices and cellular bioimaging applications.

## Abstract

Five zinc(II) complexes based on N-[[2-(p-tolylsulfonylamino)-phenyl]-methyleneamino]-4R-benzamides were synthesized and characterized by elemental analysis, ESI-MS, FT-IR, 1H NMR and single-crystal X-ray analysis. Crystallographic studies reveal that the complexes have a polymer structure in the solid state. Acylhydrazones and zinc(II) complexes demonstrate effective photoluminescence in solutions and in the solid state. Preliminary studies have shown that the studied complexes can be used as emitters in OLED devices and for the bioimaging of pathogenic processes at the cellular level.

## Linked entities

- **Chemicals:** Zinc(II) (PubChem CID 32051), 2-Tosylaminobenzaldehyde (PubChem CID 274241)

## Full-text entities

- **Genes:** LIPC (lipase C, hepatic type) [NCBI Gene 3990] {aka HDLCQ12, HL, HTGL}, ASGR1 (asialoglycoprotein receptor 1) [NCBI Gene 432] {aka ASGPR, ASGPR1, CLEC4H1, HL-1}
- **Diseases:** heart diseases (MESH:D006331), necrotic (MESH:D009336), prostate diseases (MESH:D011469), weight loss (MESH:D015431), ischemic heart (MESH:D017202), myocardial infarction (MESH:D009203), myocardial (MESH:D009202), ischemia (MESH:D007511), prostate cancer (MESH:D011471), injury to (MESH:D014947), ischemic myocardium (MESH:D017682), ischemic (MESH:D002545), cancer (MESH:D009369)
- **Chemicals:** I (MESH:D007455), CO2 (MESH:D002245), LiF (MESH:C027651), lanthanides (MESH:D028581), DMSO (MESH:D004121), DP (MESH:D004176), H (MESH:D006859), hydrazides (MESH:D006834), Zn(NO3)2 (MESH:C042103), 2-tosylaminobenzaldehyde (MESH:C572516), Na+ (MESH:D012964), imine (MESH:D007097), HEPES (MESH:D006531), K+ (MESH:D011188), azomethine (MESH:C512188), CH3O (-), O3 (MESH:D010126), Al (MESH:D000535), MoO3 (MESH:C082290), R (MESH:D001120), amine (MESH:D000588), Cl (MESH:D002713), ZnCl2 (MESH:C016837), brilliant blue (MESH:C006796), N1 (MESH:C058271), F (4) (MESH:C006011), Li+ (MESH:D008094), MB (MESH:D008751), hydrazone (MESH:D006835), F (MESH:D005461), amide (MESH:D000577), water (MESH:D014867), benzene (MESH:D001554), 2-hydroxybenzaldehydes (MESH:C013243), xenon (MESH:D014978), O (MESH:D010100), Zinc(II) (MESH:D015032), CH3OH (MESH:D000432), gold (MESH:D006046), platinum (MESH:D010984), metal (MESH:D008670), zinc acetate (MESH:D019345), C (MESH:D002244), N (MESH:D009584), CH2Cl2 (MESH:D008752)
- **Species:** Homo sapiens (human, species) [taxon 9606], Rattus norvegicus (brown rat, species) [taxon 10116]
- **Mutations:** F12K
- **Cell lines:** RWPE-1 — Homo sapiens (Human), Transformed cell line (CVCL_3791), PC-3 — Homo sapiens (Human), Prostate carcinoma, Cancer cell line (CVCL_0035), HL1- — Mus musculus (Mouse), Transformed cell line (CVCL_0303), HL1-5 — Cricetulus griseus (Chinese hamster), Hybrid cell line (CVCL_Y459)

## Full text

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## Figures

14 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12941102/full.md

## References

55 references — full list in the complete paper: https://tomesphere.com/paper/PMC12941102/full.md

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Source: https://tomesphere.com/paper/PMC12941102