# Chronic Atypical Myelomonocytic Leukemia of Eosinophilic Lineage in a Cat With Feline Leukemia Virus: A First Case Report

**Authors:** Morales Orozco Pablo José, Magaña Anzaldo Aida Evelyn, Bernal Muñoz Diana Betsabe, Saavedra Ruvalcaba Adolfo Giovanni, Rosales Camacho Paulina

PMC · DOI: 10.1155/crve/6729159 · Case Reports in Veterinary Medicine · 2026-02-26

## TL;DR

This paper reports the first case of a rare type of leukemia in a cat infected with feline leukemia virus, highlighting the importance of studying unusual cases to improve diagnosis.

## Contribution

The first documented case of atypical chronic myelomonocytic leukemia of eosinophilic lineage in a feline leukemia virus-positive cat.

## Key findings

- The case was diagnosed using detailed cytomorphological analysis and enzymatic cytochemical stains.
- The rarity of the case emphasizes the need for expanded clinical knowledge and better diagnostic tools in feline veterinary medicine.

## Abstract

Feline hematopoietic neoplasms associated with retroviruses pose a diagnostic and therapeutic challenge, especially when they present with atypical morphological features that do not fit conventional classifications. This work describes the first reported case worldwide of atypical chronic myelomonocytic leukemia of eosinophilic lineage in a cat positive for feline leukemia virus, diagnosed through detailed cytomorphological analysis and the use of enzymatic cytochemical stains. The rarity of this case underscores the importance of documenting and studying uncommon presentations, with the goal of expanding clinical knowledge and strengthening diagnostic tools in feline veterinary medicine.

## Linked entities

- **Diseases:** chronic myelomonocytic leukemia (MONDO:0011908)

## Full-text entities

- **Genes:** MPO (myeloperoxidase) [NCBI Gene 4353]
- **Diseases:** lymphadenopathy (MESH:D008206), splenomegaly (MESH:D013163), acute leukemia (MESH:D015470), Feline hematopoietic neoplasms (MESH:D019337), myelodysplastic disorder (MESH:D009190), skin masses (MESH:C536030), dysplasia (MESH:D015792), dyspnea (MESH:D004417), neoplasms (MESH:D009369), weakness (MESH:D018908), hypereosinophilia (MESH:D004802), anorexia (MESH:D000855), lymphoma (MESH:D008223), CMML (MESH:D015477), retroviral diseases (MESH:D000071297), myeloproliferative disorder (MESH:D009196), Myeloproliferative and myelodysplastic neoplasms (MESH:D054437), weight loss (MESH:D015431), cardiac murmur (MESH:D006337)
- **Chemicals:** iron (MESH:D007501), EDTA (MESH:D004492), Perl (-), lidocaine (MESH:D008012), dexmedetomidine (MESH:D020927)
- **Species:** Feline immunodeficiency virus (no rank) [taxon 11673], Feline leukemia virus (no rank) [taxon 11768], Homo sapiens (human, species) [taxon 9606], Felis catus (cat, species) [taxon 9685]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12940797/full.md

## References

4 references — full list in the complete paper: https://tomesphere.com/paper/PMC12940797/full.md

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Source: https://tomesphere.com/paper/PMC12940797