# Special Issue “Cellular and Molecular Insights into Ocular Changes Associated with Systemic Disorders and Conditions”

**Authors:** Snježana Kaštelan, Katarzyna Zorena

PMC · DOI: 10.3390/ijms27042024 · International Journal of Molecular Sciences · 2026-02-20

## Full-text entities

- **Genes:** TRPV1 (transient receptor potential cation channel subfamily V member 1) [NCBI Gene 7442] {aka VR1}, TRPV2 (transient receptor potential cation channel subfamily V member 2) [NCBI Gene 51393] {aka VRL, VRL-1, VRL1}, IL1B (interleukin 1 beta) [NCBI Gene 3553] {aka IL-1, IL1-BETA, IL1F2, IL1beta}, CCL2 (C-C motif chemokine ligand 2) [NCBI Gene 6347] {aka GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1}, FAS (Fas cell surface death receptor) [NCBI Gene 355] {aka ALPS1A, APO-1, APT1, CD95, FAS1, FASTM}, TRPV3 (transient receptor potential cation channel subfamily V member 3) [NCBI Gene 162514] {aka FNEPPK2, OLMS, OLMS1, VRL3}, TRPM8 (transient receptor potential cation channel subfamily M member 8) [NCBI Gene 79054] {aka LTRPC6, LTrpC-6, TRPP8, trp-p8}, TNFSF10 (TNF superfamily member 10) [NCBI Gene 8743] {aka APO2L, Apo-2L, CD253, TANCR, TL2, TNLG6A}, TRPV4 (transient receptor potential cation channel subfamily V member 4) [NCBI Gene 59341] {aka BCYM3, CMT2C, HMSN2C, OTRPC4, SMAL, SPSMA}, vps16 (VPS16 core subunit of CORVET and HOPS complexes) [NCBI Gene 798985] {aka im:6907749, wu:fc34a07, wu:fl62a06, zgc:162584}, TNFRSF10B (TNF receptor superfamily member 10b) [NCBI Gene 8795] {aka CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2}, CD27 (CD27 molecule) [NCBI Gene 939] {aka S152, S152. LPFS2, T14, TNFRSF7, Tp55}
- **Diseases:** oGVHD (MESH:D006086), vascular compromise (MESH:D057772), lysosomal disorders (MESH:D016464), endocrine abnormalities (MESH:D004700), Sjogren's syndrome (MESH:D012859), diabetes (MESH:D003920), endothelial dysfunction (MESH:D014652), cardiovascular and cerebrovascular disease (MESH:D002318), decline (MESH:D060825), mitochondrial dysfunction (MESH:D028361), hypomyelination (MESH:D003711), metabolic syndrome (MESH:D024821), rheumatoid arthritis (MESH:D001172), optic neuropathy (MESH:D009901), chronic systemic inflammation (MESH:D007249), injury to (MESH:D014947), neurodegeneration (MESH:D019636), papilledema (MESH:D010211), hypoxia (MESH:D000860), memory impairment (MESH:D008569), systemic diseases (MESH:D034721), systemic lupus erythematosus (MESH:D008180), systemic disorders (MESH:D009422), sleep-related breathing disorders (MESH:D012891), metabolic disorders (MESH:D008659), genetic disorders (MESH:D030342), visual field defects (MESH:D005128), upper airway obstruction (MESH:D000402), immune dysregulation (OMIM:614878), meibomian gland dysfunction (MESH:D000080343), glaucoma (MESH:D005901), autoimmune disorders (MESH:D001327), thyroid disease (MESH:D013959), neuronal death (MESH:D009410), OSA (MESH:D020181)
- **Chemicals:** Ca2+ (-), cholesterol (MESH:D002784), lipid (MESH:D008055), glutathione (MESH:D005978)
- **Species:** Homo sapiens (human, species) [taxon 9606], Danio rerio (leopard danio, species) [taxon 7955]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12940704/full.md

## References

23 references — full list in the complete paper: https://tomesphere.com/paper/PMC12940704/full.md

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Source: https://tomesphere.com/paper/PMC12940704