# Special Issue “Innovative Strategies to Target Metabolism, Inflammation, and Oxidative Stress in Human Diseases”

**Authors:** Kota V. Ramana

PMC · DOI: 10.3390/ijms27041888 · International Journal of Molecular Sciences · 2026-02-16

## Full-text entities

- **Genes:** TLR9 (toll like receptor 9) [NCBI Gene 54106] {aka CD289}, EDN1 (endothelin 1) [NCBI Gene 1906] {aka ARCND3, ET1, HDLCQ7, PPET1, QME}, MALAT1 (metastasis associated lung adenocarcinoma transcript 1) [NCBI Gene 378938] {aka HCN, LINC00047, NCRNA00047, NEAT2, PRO2853, miPEP-52}, CD4 (CD4 molecule) [NCBI Gene 920] {aka CD4mut, IMD79, Leu-3, OKT4D, T4}, CXCL8 (C-X-C motif chemokine ligand 8) [NCBI Gene 3576] {aka GCP-1, GCP1, IL8, LECT, LUCT, LYNAP}, COMT (catechol-O-methyltransferase) [NCBI Gene 1312] {aka HEL-S-98n}, SAA [NCBI Gene 6287], VEGFA (vascular endothelial growth factor A) [NCBI Gene 7422] {aka L-VEGF, MVCD1, VEGF, VPF}, DNMT1 (DNA methyltransferase 1) [NCBI Gene 1786] {aka ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT}, DNMT3A (DNA methyltransferase 3 alpha) [NCBI Gene 1788] {aka DNMT3A2, HESJAS, M.HsaIIIA, TBRS}, TACR1 (tachykinin receptor 1) [NCBI Gene 6869] {aka NK1R, NKIR, SPR, TAC1R}, MFN2 (mitofusin 2) [NCBI Gene 9927] {aka CMT2A, CMT2A2, CMT2A2A, CMT2A2B, CPRP1, HMSN6A}, TNF (tumor necrosis factor) [NCBI Gene 7124] {aka DIF, IMD127, TNF-alpha, TNFA, TNFSF2, TNLG1F}, NLRP3 (NLR family pyrin domain containing 3) [NCBI Gene 114548] {aka AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1}, IL6 (interleukin 6) [NCBI Gene 3569] {aka BSF-2, BSF2, CDF, HGF, HSF, IFN-beta-2}, CGAS (cyclic GMP-AMP synthase) [NCBI Gene 115004] {aka C6orf150, D4, MB21D1, h-cGAS}, IL1B (interleukin 1 beta) [NCBI Gene 3553] {aka IL-1, IL1-BETA, IL1F2, IL1beta}, CAT (catalase) [NCBI Gene 847]
- **Diseases:** Glaucoma (MESH:D005901), peripheral neuropathy (MESH:D010523), immune-mediated diseases (MESH:C567355), TB (MESH:D014376), Retinal Vascular Disease (MESH:D012164), bacterial (MESH:D001424), neuronal injury (MESH:D009410), type 2 diabetes (MESH:D003924), Breast Cancer (MESH:D001943), autoimmune diseases (MESH:D001327), glaucomatous damage (MESH:D020263), neuropathy (MESH:D009422), chronic diseases (MESH:D002908), pancreatic damage and dysfunction (MESH:D010182), Multiple Sclerosis (MESH:D009103), -related diseases (MESH:D000077733), neurological and blood disorders (MESH:D006425), PTSD (MESH:D013313), Allodynia (MESH:D006930), mitochondrial damage (MESH:D028361), atherosclerosis (MESH:D050197), Parkinson's (MESH:D010300), viral infections (MESH:D014777), Inflammation (MESH:D007249), Neurodegenerative Diseases (MESH:D019636), injury to (MESH:D014947), toxicity (MESH:D064420), PE (MESH:D017889), neuroinflammation (MESH:D000090862), insulin resistance (MESH:D007333), anxiety (MESH:D001007), infection (MESH:D007239), cardiovascular disease (MESH:D002318), Alzheimer's (MESH:D000544), locomotor abnormalities (MESH:D001523), Diabetic Retinopathy (MESH:D003930), cancer (MESH:D009369), Diabetes (MESH:D003920), COVID-19 (MESH:D000086382)
- **Chemicals:** lipid (MESH:D008055), Vitamin B12 (MESH:D014805), S-adenosyl-L-methionine (MESH:D012436), OH (MESH:C031356), B12 (MESH:C034730), benfotiamine (MESH:C013835), NO (MESH:D009569), glucose (MESH:D005947), peroxyl radical (MESH:C049375), hydroxyl (MESH:D017665), Copper (MESH:D003300), phosphorus (MESH:D010758), Zinc (MESH:D015032), H-Phosphinic SAM Analogue (-), O -2 (MESH:D013481), Cisplatin (MESH:D002945), VPA (MESH:D014635), acrolein (MESH:D000171), malondialdehyde (MESH:D008315), Nitrite (MESH:D009573), reactive nitrogen species (MESH:D026361), thiamine (MESH:D013831)
- **Species:** Gammacoronavirus (genus) [taxon 694013], Severe acute respiratory syndrome coronavirus 2 (no rank) [taxon 2697049], Curcuma longa (turmeric, species) [taxon 136217], Panax ginseng (Asiatic ginseng, species) [taxon 4054], Homo sapiens (human, species) [taxon 9606], Ocimum tenuiflorum (holy basil, species) [taxon 204149], Rattus norvegicus (brown rat, species) [taxon 10116], Mus musculus (house mouse, species) [taxon 10090], Mycobacterium tuberculosis (species) [taxon 1773]

## Full text

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## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12940637/full.md

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Source: https://tomesphere.com/paper/PMC12940637