# A Sophisticated Onscreen Smart Framework for Predicting Diabetes in Remote Healthcare

**Authors:** Koteeswaran Seerangan, Premalatha Gunasekaran, Nithya Rekha Sivakumar, Resmi Ravi Nair, Malarvizhi Nandagopal, Neeba Eralil Abi, Nalini Manogaran

PMC · DOI: 10.3390/diagnostics16040532 · 2026-02-11

## TL;DR

This paper introduces a new AI-based framework called BOLD for predicting diabetes efficiently in remote healthcare settings.

## Contribution

The novel BOLD framework combines optimization techniques with deep learning to improve diabetes prediction accuracy and efficiency.

## Key findings

- The BOLD model achieved high accuracy (0.996) and AUC (0.99) in diabetes prediction.
- It demonstrated excellent performance metrics including precision (0.991) and recall (0.99).
- The framework operates efficiently with a processing time of just 0.8 seconds.

## Abstract

Background/Objectives: Diabetes is one of the most familiar and common diseases among people currently, and is a type of metabolic disease that is caused due to high levels of sugar in the blood for longer periods of time. If the disease is predicted at an earlier stage, the severity and risks associated with diabetes are significantly reduced, which helps to save the lifespan of people. In earlier investigations, various kinds of automated models based on artificial intelligence (AI) were developed for this purpose. However, key issues still revolve around the lack of robustness, dependability, and precise prediction. The motivation behind the proposed study is to design and develop an automated tool for the diagnosis of chronic disease with the use of novel AI methodology. Methods: For this purpose, a new detection framework is introduced, known as the Brass Optimized Learning-Based Diabetes Prediction (BOLD) model for remote healthcare applications. By using this kind of optimization-integrated deep learning technique, the overall performance and efficiency of the diabetes detection system are maximized. This framework preprocesses the input diabetes dataset before performing the data splitting, normalization, and cleaning activities. Next, the best attributes for improving the prognostic performance of the classifier are chosen using the Brassy Pelican Optimization (BPO) procedure. The Hunting Optimized Recurrent Neural Network—Long Short-Term Memory (RNN-LSTM) method is used to categorize the people into those who are diabetic and those who are not based on the chosen attributes. The approach employs a Deer Hunting Optimization (DHO) method to choose the hyperparameters needed to make an informed choice. A variety of parameters have been employed to confirm the results, which are evaluated for performance verification using the PIDD, Indonesia diabetic database, and kidney disease dataset. Results: The BOLD framework is successful to the extent that it has been able to achieve several metrics of comparably good results, such as an RMSE value of 0.015, a Cohen’s Kappa measure of 0.99, a precision of 0.991, a recall of 0.99, an accuracy equal to 0.996, and an AUC equal to 0.99. Conclusions: It is also remarkable that a very short time of 0.8 s was enough for it to deliver this kind of performance, making it a neat combination of both time and power efficiency.

## Linked entities

- **Diseases:** diabetes (MONDO:0005015)

## Full-text entities

- **Genes:** INS (insulin) [NCBI Gene 3630] {aka IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10}
- **Diseases:** vision loss (MESH:D014786), disease (MESH:D004194), injury to (MESH:D014947), Chronic Kidney Disease (MESH:D051436), DL (MESH:C537113), polyuria (MESH:D011141), Diabetes (MESH:D003920), cancer (MESH:D009369), irritation (MESH:D001523), kidney failure (MESH:D051437), ML (MESH:C537366), stroke (MESH:D020521), retinopathy (MESH:D058437), alopecia (MESH:D000505), obesity (MESH:D009765), itching (MESH:D011537), metabolic disease (MESH:D008659), death (MESH:D003643), polydipsia (MESH:D059606), cardiovascular disorders (MESH:D002318), infected (MESH:D007239), coronary artery disease (MESH:D003324), cardiac disease (MESH:D006331), organ damage (MESH:D000092124), digestive and kidney disease (MESH:D007674), type 2 diabetes (MESH:D003924), chronic illness (MESH:D002908), neuropathy (MESH:D009422), diabetic kidney disease (MESH:D003928)
- **Chemicals:** sugar (MESH:D000073893), BPA (MESH:C006780), BOLD (-), Glucose (MESH:D005947)
- **Species:** Cheloniidae (sea turtles, family) [taxon 8465], Homo sapiens (human, species) [taxon 9606], Pelecanidae (pelicans, family) [taxon 30444], Odocoileus virginianus (white-tailed deer, species) [taxon 9874], Cervidae (deer, family) [taxon 9850]
- **Cell lines:** LSTM — Anopheles stephensi (Indo-Pakistan malaria mosquito), Spontaneously immortalized cell line (CVCL_Z358)

## Figures

26 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12940048/full.md

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Source: https://tomesphere.com/paper/PMC12940048