# Awareness and Perceived Risk Factors of Chronic Kidney Disease Among Patients with Diabetes in the Northern Borders of Saudi Arabia: Implications for a Strategic Monitoring and Management Plan

**Authors:** Safya E. Esmaeel, Altaf Saleh Mahdi Alanazi Alnzi, Nouf Mofareh Mulahed Alanazi, Rose Dahi Khamis Alanazi, Amal Mohammed Shahi Alruwaili, Areeb Rawaf Mohammed Alanzi, Ahad Wadi Alnagzi Alanazi, Yousef Wasmi Alenezi, Ahmed Saleh Alanazi, Rimas Khalid A. Alanazi, Baraah Abu Alsel, Eslam K. Fahmy, Manal S. Fawzy

PMC · DOI: 10.3390/diseases14020074 · 2026-02-16

## TL;DR

This study examines CKD awareness and risk factors among diabetic patients in Saudi Arabia's Northern Borders to inform better monitoring and management strategies.

## Contribution

The study provides region-specific insights into CKD awareness and risk factors among diabetic patients in Saudi Arabia.

## Key findings

- 46.8% of participants demonstrated good awareness of CKD.
- Hypertension and heart disease were strongly associated with self-reported CKD.
- Males and unmarried individuals showed higher CKD awareness.

## Abstract

Background/Objectives: Chronic kidney disease (CKD) poses a significant health burden for individuals with diabetes mellitus, increasing morbidity and mortality. Understanding CKD and its risk factors is essential for early detection, effective management, and prevention of complications. This study aimed to assess CKD awareness as the primary outcome and to explore self-reported CKD prevalence and associated factors as secondary outcomes among patients with diabetes in the Northern Border Region, Saudi Arabia. Methods: A cross-sectional survey was conducted among 389 adults with a self-reported physician diagnosis of diabetes in the specified region, using a validated, self-administered online questionnaire. Data were analyzed to evaluate CKD awareness and identify perceived risk factors and factors associated with self-reported CKD. Results: Of the participants, 182 (46.8%) demonstrated good awareness of CKD, while the self-reported prevalence of CKD was 83 (21.3%). Males and unmarried participants were more likely to have good CKD awareness (p = 0.008 and 0.009, respectively). Significant associations were observed between self-reported CKD prevalence and age, sex, type of diabetes, family history of kidney disease, and comorbidities (all p < 0.05). Multivariate logistic regression showed that hypertension was strongly associated with self-reported CKD [aOR = 5.77; 95% CI: 3.12–10.67; p < 0.001], as was heart disease [aOR = 4.21; 95% CI: 1.35–13.13; p = 0.013]. Conclusions: Patients with diabetes in this region exhibited moderate awareness of CKD, with higher awareness among males and unmarried individuals. Hypertension and cardiac disease were significantly associated with self-reported CKD. These findings underscore the importance of targeted education, routine evidence-based screening, and structured management strategies for CKD within diabetes care and provide a basis for a regional strategic plan to strengthen CKD monitoring among patients with diabetes.

## Linked entities

- **Diseases:** Chronic kidney disease (MONDO:0005300), diabetes mellitus (MONDO:0005015), heart disease (MONDO:0005267)

## Full-text entities

- **Genes:** ALB (albumin) [NCBI Gene 213] {aka FDAHT, HSA, PRO0883, PRO0903, PRO1341}
- **Diseases:** metabolic abnormalities (MESH:D008659), diabetic kidney disease (MESH:D003928), eye complications (MESH:D005128), neuropathy (MESH:D009422), infectious diseases (MESH:D003141), chronic diseases (MESH:D002908), T2DM (MESH:D003924), Kidney Disease (MESH:D007674), obesity (MESH:D009765), noncommunicable diseases (MESH:D000073296), cardiac disease (MESH:D006331), coronary artery disease (MESH:D003324), type 1 diabetes (MESH:D003922), cardiovascular disease (MESH:D002318), decline of renal function (MESH:D060825), kidney failure (MESH:D051437), ESRD (MESH:D007676), DM (MESH:D003920), CKD (MESH:D051436), complication (MESH:D008107), injury to (MESH:D014947), diabetic foot (MESH:D017719), cardiometabolic diseases (MESH:D024821), albuminuria (MESH:D000419), malnutrition (MESH:D044342), death (MESH:D003643), dyslipidemia (MESH:D050171), pain (MESH:D010146), Hypertension (MESH:D006973)
- **Chemicals:** creatinine (MESH:D003404), blood sugar (MESH:D001786), oral antidiabetic medications (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12939839/full.md

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Source: https://tomesphere.com/paper/PMC12939839