Clinical Application of an Oral Liquid Bandage (ORAPLA) for Traumatic and Surgical Oral Mucosal Wounds: A Technical Note
Hiroshi Furuta, Atsushi Abe, Shoya Mizuno, Sayaka Furuhashi, Sayumi Hiraguri, Moeko Momokita, Tetsushi Oguma, Atsushi Nakayama, Hiroki Inoue

TL;DR
This paper explores the use of ORAPLA, an oral liquid bandage, to manage oral mucosal wounds and finds it provides immediate pain relief and protection.
Contribution
The study introduces ORAPLA as a practical clinical solution for managing oral mucosal wounds with immediate protective effects.
Findings
ORAPLA formed a protective film that lasted 5–6 hours and was well tolerated.
Patients experienced prompt pain relief with no adverse events observed.
Epithelialization occurred without secondary infection during follow-up.
Abstract
Background/Objectives: Oral mucosal wounds are frequently encountered in daily dental practice and are often difficult to manage because of continuous exposure to saliva, mastication, and mechanical irritation. This technical note describes the clinical practicality of an oral liquid bandage (ORAPLA) as a film-forming protective barrier for traumatic and surgical oral mucosal wounds. Methods: ORAPLA was applied in four clinical scenarios: a traumatic lip bite injury, a postoperative mucosal defect following leukoplakia excision, a biopsy wound for suspected oral squamous cell carcinoma (OSCC), and aphthous stomatitis. Clinical observations included patient-reported symptom relief, film retention, and the clinical appearance of epithelialization at follow-up (1–2 weeks). Results: In all cases, ORAPLA formed a thin protective film immediately after application and was typically observed…
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Taxonomy
TopicsOral Health Pathology and Treatment · Oral health in cancer treatment · Salivary Gland Disorders and Functions
