# Short-Wave Infrared Reflectance at 1050–1550 nm for Proximal Caries Detection: An In Vitro Diagnostic Accuracy Study Validated by Micro-CT

**Authors:** Friederike Litzenburger, Karl-Heinz Kunzelmann, Elias Walter, Falk Schwendicke, Katrin Heck

PMC · DOI: 10.3390/diagnostics16040548 · Diagnostics · 2026-02-12

## TL;DR

This study evaluates short-wave infrared reflectance imaging for detecting tooth decay, finding that a wavelength of 1050 nm offers the best balance of accuracy and reliability.

## Contribution

The study systematically evaluates the impact of wavelength selection on SWIRR diagnostic accuracy for proximal caries detection.

## Key findings

- SWIRR diagnostic performance varies with wavelength, showing higher sensitivity at longer wavelengths.
- 1050 nm SWIRR achieved the highest overall accuracy (80.0%) compared to digital bitewing radiography (73.8%).
- 1550 nm SWIRR had the highest sensitivity but increased false positives.

## Abstract

Background/Objectives: Short-wave infrared reflectance (SWIRR) imaging is a non-ionising approach for proximal caries detection; however, the diagnostic impact of wavelength selection in reflectance imaging has not been systematically evaluated. Methods: This in vitro diagnostic accuracy study assessed SWIRR at 1050, 1200, 1300 and 1550 nm for proximal caries detection, using micro-computed tomography as the reference standard and digital bitewing radiography (BWR) as the clinical comparator. A total of 250 extracted permanent posterior teeth with sound or carious proximal surfaces were examined. SWIRR and BWR images were independently evaluated twice by two calibrated examiners using method-specific criteria. Diagnostic performance was quantified by sensitivity, specificity and accuracy; examiner reliability was analysed using kappa statistics, and pairwise comparisons were performed using McNemar tests with Holm–Bonferroni correction. Results: Diagnostic performance of SWIRR was wavelength dependent, showing increasing sensitivity and decreasing specificity with longer wavelengths. The highest overall accuracy was observed at 1050 nm (80.0%), exceeding that of BWR (73.8%) while maintaining comparable specificity and higher sensitivity. At 1550 nm, sensitivity was highest but accompanied by an increase in false-positive findings. Conclusions: SWIRR demonstrates high diagnostic potential for proximal caries detection, with 1050 nm providing the most favourable balance between diagnostic accuracy and specificity.

## Full-text entities

- **Diseases:** lesion (MESH:D009059), injury to (MESH:D014947), enamel lesions (MESH:D003744), caries (MESH:D003731)
- **Chemicals:** sodium azide (MESH:D019810), water (MESH:D014867), BH (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

36 references — full list in the complete paper: https://tomesphere.com/paper/PMC12939269/full.md

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Source: https://tomesphere.com/paper/PMC12939269