# Peri-Implantitis—An Overview of Treatment Options and a New Approach to the Treatment of Peri-Implantitis Using a Magnesium Membrane in Three Case Reports

**Authors:** Domagoj Vražić, Katarina Komar Milas, Marko Blašković, Ivana Butorac Prpić, Marija Čandrlić, Željka Perić Kačarević

PMC · DOI: 10.3390/dj14020112 · Dentistry Journal · 2026-02-13

## TL;DR

This paper reviews treatment options for peri-implantitis and introduces a new method using a magnesium membrane in three clinical cases.

## Contribution

A novel clinical approach using a resorbable magnesium membrane combined with a bovine xenograft is introduced and tested in case reports.

## Key findings

- Three clinical cases showed favorable outcomes using a magnesium membrane and bovine xenograft.
- The new approach allowed bone defect reconstruction without implant removal in one case.
- The minimally invasive shield technique demonstrated success without removing the implant or crown.

## Abstract

Background/Objectives: Dental implants are a preferred solution for missing teeth, but peri-implantitis remains a major challenge in implant dentistry. This narrative review provides an overview of the therapeutic interventions for peri-implantitis based on the current literature and illustrates a new clinical approach using novel magnesium membrane through three case presentations. Methods: A comprehensive literature search on peri-implantitis management was conducted, with emphasis on current clinical practice guidelines. In addition, three clinical cases were presented to demonstrate the use of a fully resorbable magnesium membrane in combination with a bovine xenograft with hyaluronate. Results: The narrative review identified and summarized a wide range of non-surgical and surgical therapeutic strategies for treatment of peri-implantitis. Additionally, three case reports with novel magnesium membrane highlighted distinct clinical scenarios: (1) bone defect reconstruction without implant removal, (2) reconstruction following implant removal, and (3) a minimally invasive shield technique performed without removal of the implant or crown. All cases demonstrated favorable clinical outcomes following the novel biomaterial approach. Conclusions: The combination of a resorbable magnesium membrane with bovine xenograft with hyaluronate represents a promising therapeutic strategy for treatment of peri-implantitis. This approach may improve clinical outcomes and potentially set new standards in implant dentistry. Further studies with larger cohorts and control groups are required to confirm these preliminary findings.

## Full-text entities

- **Genes:** IL1B (interleukin 1 beta) [NCBI Gene 281251]
- **Diseases:** injury to (MESH:D014947), inflammation (MESH:D007249), periodontitis (MESH:D010518), fracture (MESH:D050723), dehiscence (MESH:D013529), bleeding (MESH:D006470), infection (MESH:D007239), bone (MESH:D001847), Peri-Implantitis (MESH:D057873), allergies (MESH:D004342)
- **Chemicals:** PTFE (MESH:D011138), carbon (MESH:D002244), polymers (MESH:D011108), epinephrine (MESH:D004837), articaine (MESH:D002355), chlorhexidine digluconate (MESH:C010882), hydroxyl (MESH:D017665), hyaluronate (MESH:D006820), Amoksicilin (-), titanium (MESH:D014025), Cerabone (MESH:C000593119), PLA (MESH:C033616), Parodontax (MESH:C091016), hydrogen (MESH:D006859), Magnesium (MESH:D008274), PGA (MESH:D011454)
- **Species:** Treponema denticola (species) [taxon 158], Porphyromonas gingivalis (species) [taxon 837], Tannerella forsythia (species) [taxon 28112], Homo sapiens (human, species) [taxon 9606], Bos taurus (bovine, species) [taxon 9913]

## Full text

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## Figures

11 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12939063/full.md

## References

65 references — full list in the complete paper: https://tomesphere.com/paper/PMC12939063/full.md

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Source: https://tomesphere.com/paper/PMC12939063