# The Many Faces of Glioblastoma-Associated Macrophages and Their Gene Signatures

**Authors:** Mikael S. Lindström

PMC · DOI: 10.3390/cancers18040624 · Cancers · 2026-02-14

## Full-text entities

- **Genes:** ADM (adrenomedullin) [NCBI Gene 133] {aka AM, PAMP}, TYMS (thymidylate synthetase) [NCBI Gene 7298] {aka DKCD, HST422, TMS, TS}, MKI67 (marker of proliferation Ki-67) [NCBI Gene 4288] {aka KIA, MIB-, MIB-1, PPP1R105}, PDCD1 (programmed cell death 1) [NCBI Gene 5133] {aka ADMIO4, AIMTBS, CD279, PD-1, PD1, SLEB2}, THEMIS2 (thymocyte selection associated family member 2) [NCBI Gene 9473] {aka C1orf38, ICB-1, ICB1}, MGMT (O-6-methylguanine-DNA methyltransferase) [NCBI Gene 4255], MS4A6A (membrane spanning 4-domains A6A) [NCBI Gene 64231] {aka 4SPAN3, 4SPAN3.2, CD20L3, CDA01, MS4A6, MST090}, APOE (apolipoprotein E) [NCBI Gene 348] {aka AD2, APO-E, ApoE4, LDLCQ5, LPG}, SIGLEC9 (sialic acid binding Ig like lectin 9) [NCBI Gene 27180] {aka CD329, CDw329, FOAP-9, OBBP-LIKE, siglec-9}, HDAC8 (histone deacetylase 8) [NCBI Gene 55869] {aka CDA07, CDLS5, HD8, HDACL1, KDAC8, MRXS6}, CSTA (cystatin A) [NCBI Gene 1475] {aka AREI, PSS4, STF1, STFA}, IGF1R (insulin like growth factor 1 receptor) [NCBI Gene 3480] {aka CD221, IGFIR, IGFR, JTK13}, TAM (Myeloproliferative syndrome, transient (transient abnormal) [NCBI Gene 8205] {aka MST}, CSF1R (colony stimulating factor 1 receptor) [NCBI Gene 1436] {aka BANDDOS, C-FMS, CD115, CSF-1R, CSFR, FIM2}, IDH1 (isocitrate dehydrogenase (NADP(+)) 1) [NCBI Gene 3417] {aka HEL-216, HEL-S-26, IDCD, IDH, IDP, IDPC}, LILRB3 (leukocyte immunoglobulin like receptor B3) [NCBI Gene 11025] {aka CD85A, HL9, ILT-5, ILT5, LIR-3, LIR3}, STMN1 (stathmin 1) [NCBI Gene 3925] {aka C1orf215, LAP18, Lag, OP18, PP17, PP19}
- **Diseases:** injury to (MESH:D014947), glioma (MESH:D005910), Tumor (MESH:D009369), hypoxic (MESH:D002534), hypoxia (MESH:D000860), MAPS (MESH:D055501), lipid (MESH:D011017), necrosis (MESH:D009336), GBM (MESH:D005909)
- **Chemicals:** vincristine (MESH:D014750), SCH772984 (MESH:C587178), sepantronium bromide (MESH:C523798), tozasertib (MESH:C484810), BMS-536924 (MESH:C504983), selumetinib (MESH:C517975), PCI-34051 (MESH:C529435), lipid (MESH:D008055)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

42 references — full list in the complete paper: https://tomesphere.com/paper/PMC12939019/full.md

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Source: https://tomesphere.com/paper/PMC12939019