# A Review of Motion-Preserving Cervical Spinal Implants and Fusion Constructs

**Authors:** Isabella Merem, Rodrigo Vasquez, Jaden Wise, Elizabeth Beaulieu, Samip Patel, Maohua Lin, Gui Pires, Frank D. Vrionis

PMC · DOI: 10.3390/bioengineering13020228 · Bioengineering · 2026-02-15

## TL;DR

This review compares spinal fusion and motion-preserving implants in the cervical spine, highlighting biomechanical differences and the potential benefits of motion-preserving devices.

## Contribution

The paper provides a comprehensive synthesis of experimental, computational, and clinical studies comparing fusion and motion-preserving cervical spine implants.

## Key findings

- Cervical disc arthroplasty (CDA) preserves near-physiologic motion better than fusion constructs.
- Motion-preserving implants alter load transmission and facet joint forces differently compared to fusion.
- Biomechanics-informed design is critical for optimizing motion-preserving spinal implants.

## Abstract

Spinal fusion remains a common surgical treatment for degenerative cervical spine pathology. By eliminating segmental motion, fusion alters spinal biomechanics and redistributes mechanical loads to adjacent levels. These changes contribute to adjacent segment degeneration (ASD). Motion-preserving spinal implants have been developed to address these limitations. Cervical disc arthroplasty (CDA) is the most widely used example. Such devices aim to maintain physiologic kinematics while preserving segmental stability. Their biomechanical behavior varies with implant design, material properties, and constraint characteristics. Previous research does not holistically compare fusion with motion-preserving treatments on the spine, resulting in an incomplete understanding of when motion-preserving devices should be considered in treatment over fusion constructs and which specific motion-preserving implants are most appropriate. This narrative review synthesizes experimental, computational, and clinical studies comparing rigid fusion constructs to motion-preserving technologies in the cervical spine. Emphasis is placed on segmental range of motion, load transmission, intradiscal pressure, facet joint forces, and adjacent-segment mechanics. By comparing effectiveness across motion-preserving treatments, alongside their effectiveness to fusion constructs, we found that CDA more closely preserves near-physiologic motion compared to fusion. Taken together, this review underscores the importance of biomechanics-informed implant design for guiding future innovation in spinal implant technologies.

## Full-text entities

- **Genes:** IDH1 (isocitrate dehydrogenase (NADP(+)) 1) [NCBI Gene 3417] {aka HEL-216, HEL-S-26, IDCD, IDH, IDP, IDPC}, TNFRSF11B (TNF receptor superfamily member 11b) [NCBI Gene 4982] {aka OCIF, OPG, PDB5, TR1}
- **Diseases:** TDR (MESH:D055959), ASD (MESH:C537538), kyphotic curvature (MESH:D013121), axial rotation (MESH:C537791), spine (MESH:D016135), HO (MESH:D009999), myelopathy (MESH:D013118), ROM (MESH:D010033), Hypermobility (MESH:C536196), degenerative cervical spine pathology (MESH:D002575), injury to (MESH:D014947), pain (MESH:D010146), fusion (MESH:D000069337), neural compression (MESH:D009408), reduced (MESH:D001523), radiculopathy (MESH:D011843), osteoporotic bone (MESH:D058866)
- **Chemicals:** Mobi-C (MESH:D000077239), CDA (-), Ti (MESH:D014025), polyethylene (MESH:D020959), steel (MESH:D013232), PEEK (MESH:C063834)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12938692/full.md

## References

78 references — full list in the complete paper: https://tomesphere.com/paper/PMC12938692/full.md

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Source: https://tomesphere.com/paper/PMC12938692