# Inception U-Net for Enhanced Breast Ultrasound Image Segmentation Using Transfer Learning

**Authors:** Yeonhyo Choi, Myoung Nam Kim, Sungdae Na

PMC · DOI: 10.3390/bioengineering13020181 · Bioengineering · 2026-02-04

## TL;DR

This paper introduces an improved U-Net model using Inception architecture and transfer learning to better segment breast ultrasound images, achieving better performance than traditional methods.

## Contribution

The novel use of Inception modules in U-Net and transfer learning from ImageNet for breast ultrasound segmentation.

## Key findings

- The Inception U-Net achieved an IoU score of 0.7774, outperforming the baseline U-Net by about 5%.
- The model showed improved precision and recall scores, indicating better segmentation accuracy.
- Transfer learning from ImageNet proved effective despite domain differences in medical imaging.

## Abstract

Background: Breast cancer diagnosis increasingly relies on ultrasound imaging, but challenges related to operator dependency and image quality limitations necessitate automated segmentation approaches. Traditional U-Net architectures, while widely used for medical image segmentation, suffer from shallow encoder structures that limit feature extraction capabilities. Methods: This study proposes an enhanced segmentation model that replaces the conventional U-Net encoder with an Inception architecture and employs transfer learning using ImageNet pre-trained weights. The model was trained and evaluated on a dataset of 900 breast ultrasound images from Kyungpook National University Hospital. Performance evaluation utilized multiple metrics including Intersection over Union (IoU), Dice coefficient, precision, and recall scores. Results: The proposed Inception U-Net achieved superior performance with an IoU score of 0.7774, Dice score of 0.8491, precision score of 0.7081, and recall score of 0.7174, demonstrating approximately 5% improvement over baseline U-Net architecture across all evaluation metrics. Conclusions: The integration of Inception modules within the U-Net architecture effectively addresses feature extraction limitations in breast ultrasound segmentation. Transfer learning from ImageNet datasets proves beneficial even across domain differences, establishing a foundation for broader medical imaging applications.

## Linked entities

- **Diseases:** breast cancer (MONDO:0004989)

## Full-text entities

- **Diseases:** lesion (MESH:D009059), malignancies (MESH:D009369), injury to (MESH:D014947), Breast cancer (MESH:D001943)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

33 references — full list in the complete paper: https://tomesphere.com/paper/PMC12938508/full.md

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Source: https://tomesphere.com/paper/PMC12938508