# Bilateral elbow joint osteonecrosis reconstructed by custom distal humerus hemiarthroplasty and megaprosthesis with tendon and nerve transfers – A case report

**Authors:** Yannick Albert J. Hoftiezer, Joseph O. Werenski, Carolina Posada Alvarez, Sang-Gil Lee, Santiago A. Lozano-Calderón

PMC · DOI: 10.1016/j.jpra.2026.01.039 · JPRAS Open · 2026-01-31

## TL;DR

A patient with severe elbow joint damage from cancer treatment was successfully treated with custom implants and nerve/tendon transfers, allowing her to regain function and continue caregiving.

## Contribution

A novel combined orthoplastic approach using custom implants and nerve/tendon transfers for complex bilateral elbow osteonecrosis.

## Key findings

- Custom implants preserved weight-bearing capacity in the dominant arm, avoiding typical post-surgery restrictions.
- Bilateral upper extremity function was restored with minimal pain at 2 years post-treatment.
- Nerve decompression and transfers effectively addressed high radial nerve palsy.

## Abstract

We present the case of a patient with bilateral distal humerus osteonecrosis following chemoradiation for lymphoma. Treatment consisted of a right total elbow arthroplasty with a distal humerus megaprosthesis and a left custom-made distal humerus hemiarthroplasty, replacing exclusively the humeral articular cartilage while preserving the native medial and lateral humeral columns. By using a custom implant of this design, we were able to avoid the weight-bearing and lifting restrictions to which patients have to adhere following a typical total elbow arthroplasty. Thus, we were able to preserve weight-bearing capacity in the dominant arm of the patient, which she required to act as a caregiver to a disabled family member. The case was complicated by a concurrent high radial nerve palsy which was treated by nerve decompression and transfers of tendons and nerves. Ultimately, bilateral upper extremity function was good with negligible pain at 2 years of follow-up. In conclusion, this case demonstrates the value of a combined orthoplastic approach and custom implants in successfully reconstructing complex upper extremity defects such as bilateral elbow joint osteonecrosis.

## Linked entities

- **Diseases:** lymphoma (MONDO:0003659)

## Full-text entities

- **Diseases:** alcoholism (MESH:D000437), aseptic loosening (MESH:D011475), pain (MESH:D010146), fracture (MESH:D050723), Osteonecrosis (MESH:D010020), B-cell lymphoma (MESH:D016393), lymphoma (MESH:D008223), distal humerus (MESH:D000092483), proximal radial nerve palsy (MESH:D020425), nerve defects (MESH:C537568), Disabilities of the Arm, Shoulder and Hand (MESH:D012019), osteoarthritis (MESH:D010003), elbow joint osteonecrosis (MESH:D000092464), loss of function of the hand (MESH:D006230)
- **Chemicals:** steroid (MESH:D013256), calcium sulfate (MESH:D002133)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12938139/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12938139/full.md

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Source: https://tomesphere.com/paper/PMC12938139