# Nanoplatforms for Multimodal Imaging and Targeted Cancer Therapy: Recent Advances and Future Perspectives

## TL;DR

This paper reviews recent advances in nanoplatforms that combine cancer imaging and therapy, offering more precise and effective treatment options.

## Contribution

The paper highlights novel nanomaterials and their multifunctional capabilities for enhanced cancer diagnosis and treatment.

## Key findings

- Gold-based and iron oxide nanoparticles improve tumor imaging and photothermal therapy.
- Polymeric and silica-based nanoplatforms enable targeted drug delivery and reduced side effects.
- Graphene oxide systems support subcellular targeting and synergistic therapeutic approaches.

## Abstract

Recent advancements in nanotechnology have led to the development of multifunctional nanoplatforms that significantly enhance both cancer diagnosis and treatment. Gold-based nanoparticles, such as peptide-functionalized nanostructures and PEG-coated nanorods, offer improved tumor targeting, multimodal imaging (including photoacoustic and fluorescence), and effective photothermal therapy. Similarly, ultrafine iron oxide nanoprobes provide superior tumor imaging, while silver-based nanoparticles exhibit rapid systemic circulation, near-infrared fluorescence, and powerful photothermal properties. Titanium-based nanoplatforms enable a combination of therapies and advanced imaging methods. On the therapeutic side, polymeric nanoparticles (PNPs), silica-based platforms, PEG-based nanoparticles, and graphene oxide-based systems each offer unique advantages for targeted drug delivery and theranostics. PNPs, with tunable size, shape, and surface chemistry, enable controlled drug release and reduced side effects, while silica-based nanoplatforms improve tumor targeting and imaging. PEG-based nanoparticles enhance drug release and tumor penetration, and graphene oxide-based systems facilitate subcellular targeting and synergistic therapies. Collectively, these innovations are paving the way for more efficient, precise, and safer cancer therapies, leading to improved clinical outcomes.