# Adult Ileocolic Intussusception Secondary to Appendiceal Mucocele: A Report of a Rare Case

**Authors:** Ibrahim Y Kutbi, Faris A Zaini, Mohammed A Alnafisah, Hassan A Alherz, Anas E Ahmed

PMC · DOI: 10.7759/cureus.102390 · Cureus · 2026-01-27

## TL;DR

A rare case of adult ileocolic intussusception caused by an appendiceal mucocele is reported, emphasizing the importance of accurate diagnosis and careful surgical management.

## Contribution

This case report highlights the rare association of appendiceal mucocele with adult intussusception and underscores the need for precise imaging and surgical techniques.

## Key findings

- Laparoscopic-assisted right hemicolectomy successfully treated the intussusception and mucocele without rupture.
- Histopathology confirmed a low-grade appendiceal mucinous neoplasm with no invasion or lymphovascular involvement.
- The patient had an uneventful recovery with no recurrence or complications at follow-up.

## Abstract

Adult intussusception is a rare and diagnostically challenging condition, often caused by an underlying pathological lead point such as neoplasms, with presentations that are typically nonspecific and intermittent, including abdominal pain, nausea, vomiting, and altered bowel habits. Among unusual causes, appendiceal mucoceles represent a rare but clinically significant entity that can precipitate intussusception, carrying a risk of serious complications like pseudomyxoma peritonei (PMP) if ruptured. We report the case of a 58-year-old male presenting with right lower quadrant pain, nausea, and intermittent bowel habit changes, in whom imaging revealed ileocolic intussusception with a cystic lesion suggestive of an appendiceal mucocele. The patient underwent laparoscopic-assisted right hemicolectomy, with en bloc resection of the intussuscepted segment and mucocele, avoiding rupture. Histopathology confirmed a low-grade appendiceal mucinous neoplasm without invasion or lymphovascular involvement. The patient recovered uneventfully, and follow-up demonstrated no recurrence or complications. This report highlights the importance of high-resolution imaging in identifying both intussusception and its lead point, the necessity of maintaining suspicion for neoplastic causes in adults, and the critical role of careful surgical management to prevent morbidity and ensure favorable outcomes.

## Linked entities

- **Diseases:** intussusception (MONDO:0007835), appendiceal mucocele (MONDO:0001671), pseudomyxoma peritonei (MONDO:0017048)

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}, mucin [NCBI Gene 100508689]
- **Diseases:** duplication cyst (MESH:D003560), acute abdomen (MESH:D000006), gastrointestinal bleeding (MESH:D006471), constipation (MESH:D003248), tenderness (MESH:D063806), gastrointestinal malignancies (MESH:D005770), polyps (MESH:D011127), weight loss (MESH:D015431), peritoneal (MESH:D010538), infection (MESH:D007239), mucinous (MESH:D002288), Ileocolic Intussusception (MESH:D003424), retention (MESH:D016055), PMP (MESH:D011553), hypertension (MESH:D006973), Intussusception (MESH:D007443), cecal or appendiceal neoplasm (MESH:D002430), metastases (MESH:D009362), vomiting (MESH:D014839), Appendiceal mucocele (MESH:D009078), inflammatory masses (MESH:C536030), fever (MESH:D005334), appendiceal abscess (MESH:D001063), jaundice (MESH:D007565), nausea (MESH:D009325), lymphadenopathy (MESH:D008206), anorexia (MESH:D000855), edematous (MESH:D004487), pneumoperitoneum (MESH:D011027), abdominal pain (MESH:D015746), Tumor (MESH:D009369), rupture (MESH:D012421), hepatosplenomegaly (MESH:C535727), mucinous lesion (MESH:D018297), pain (MESH:D010146), Inflammatory (MESH:D007249), bowel obstruction (MESH:D012778)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12937959/full.md

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Source: https://tomesphere.com/paper/PMC12937959