# Posterior Reversible Encephalopathy Syndrome Caused by Renovascular Hypertension in a Solitary Functioning Kidney: Successful Treatment With Renal Artery Stenting

**Authors:** Hiromichi Ueno, Tetsu Miyamoto, Yuki Tsuda, Masaharu Kataoka

PMC · DOI: 10.7759/cureus.102381 · Cureus · 2026-01-27

## TL;DR

An elderly woman with a single functioning kidney developed neurological symptoms due to severe hypertension caused by kidney artery blockage, which was successfully treated with a stent.

## Contribution

This case highlights renovascular hypertension as a reversible cause of PRES in patients with a solitary kidney.

## Key findings

- The patient's PRES was linked to renovascular hypertension in a solitary functioning kidney.
- Renal artery stenting stabilized blood pressure and resolved neurological symptoms.
- The case emphasizes the importance of diagnosing renovascular causes in PRES patients with marked hypertension.

## Abstract

Posterior reversible encephalopathy syndrome (PRES) can develop in the setting of severe hypertension and may present with seizures and altered consciousness. We report the case of an 81-year-old woman who presented with impaired consciousness and generalized seizures during a hypertensive crisis. Brain magnetic resonance imaging revealed bilateral parieto-occipital subcortical hyperintensities. Diagnostic imaging revealed severe proximal stenosis of the right renal artery, complete occlusion of the left renal artery, and marked atrophy of the left kidney, suggesting renovascular hypertension due to renal artery stenosis in a solitary functioning kidney. Based on these findings, PRES secondary to renovascular hypertension was diagnosed, and percutaneous renal angioplasty was performed, resulting in stabilization of blood pressure and resolution of neurological symptoms. This case highlights the importance of considering renovascular hypertension as a reversible cause of PRES, especially in patients with a solitary kidney and marked blood pressure elevation and variability.

## Linked entities

- **Diseases:** Posterior reversible encephalopathy syndrome (MONDO:0044033), renovascular hypertension (MONDO:0001105)

## Full-text entities

- **Genes:** REN (renin) [NCBI Gene 5972] {aka ADTKD4, HNFJ2, RTD}
- **Diseases:** ostial stenosis (MESH:D003251), neurological and renal dysfunction (MESH:D009461), seizures (MESH:D012640), deterioration of renal function (MESH:D058186), autoimmune diseases (MESH:D001327), nausea (MESH:D009325), hemorrhage (MESH:D006470), vasogenic edema (MESH:D001929), chronic kidney disease (MESH:D051436), atrophy (MESH:D001284), cytotoxic drug (MESH:D000092582), pulmonary edema (MESH:D011654), endothelial dysfunction (MESH:D014652), renal failure (MESH:D051437), neurotoxic (MESH:D020258), visual disturbance (MESH:D014786), headache (MESH:D006261), cerebral complications (MESH:D008107), neurologic sequelae (MESH:D009422), PRES (MESH:D054038), infarction (MESH:D007238), atrophy of the left kidney (MESH:D007674), murmur (MESH:D006337), Artery (MESH:D012078), Renovascular Hypertension (MESH:D006978), Renal Atherosclerotic Lesions (MESH:D050197), hypertension (MESH:D006973), neurological damage (MESH:D020196), altered consciousness (MESH:D003244)
- **Chemicals:** aldosterone (MESH:D000450), nicardipine (MESH:D009529), nifedipine (MESH:D009543), oxygen (MESH:D010100), salt (MESH:D012492), azilsartan (MESH:C521273), creatinine (MESH:D003404), trichlormethiazide (MESH:D014237), benidipine (MESH:C061004), PTRA (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12937958/full.md

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Source: https://tomesphere.com/paper/PMC12937958