# Complexities of Occult and Obscure Gastrointestinal Bleeding: A Case Report

**Authors:** Anna Mealy, Joseph Jaya, Zacch Ray Yan Seah, Geraldine Ooi

PMC · DOI: 10.7759/cureus.102391 · Cureus · 2026-01-27

## TL;DR

This case report discusses the challenges of diagnosing and managing obscure gastrointestinal bleeding caused by small-bowel vascular malformations.

## Contribution

The paper presents a rare case of multiple small-bowel vascular malformations causing recurrent iron deficiency anemia.

## Key findings

- The patient required monthly iron infusions due to recurrent iron deficiency anemia.
- Multiple diagnostic modalities revealed multiple small-bowel vascular malformations as the cause.
- A multidisciplinary approach is essential for managing such complex cases.

## Abstract

Small-bowel vascular malformations represent an uncommon but important source of obscure bleeding that can lead to iron deficiency anemia. Diagnosis and management can be challenging due to the intermittent nature and inaccessibility of small-bowel lesions. We present a 36-year-old man with recurrent iron deficiency anemia (IDA) requiring monthly iron infusions, in whom investigations using multiple modalities revealed the unusual finding of multiple small-bowel vascular malformations. Extensive investigations have failed to definitively localize a culprit bleeding point. This case highlights the diagnostic complexity of occult small-bowel bleeding and highlights the need for a coordinated multidisciplinary approach to establish an optimal management strategy.

## Linked entities

- **Diseases:** iron deficiency anemia (MONDO:0001356)

## Full-text entities

- **Diseases:** blue nevi (MESH:D018329), pernicious anemia (MESH:D000752), IDA (MESH:D018798), epistaxis (MESH:D004844), Small-bowel vascular malformations (MESH:D054079), Dieulafoy's lesion (MESH:D009059), bleeding (MESH:D006470), VCE (MESH:D002062), blood loss (MESH:D016063), Small-bowel vascular lesions (MESH:D014652), tumors (MESH:D009369), epigastric pain (MESH:D010146), angiodysplasia (MESH:D016888), paroxysmal nocturnal hemoglobinuria (MESH:D006457), short-bowel syndrome (MESH:D012778), cirrhosis (MESH:D005355), GI bleeding (MESH:D006471), vascular anomalies (MESH:D020785), serosal ectasia (MESH:D012700), bruising (MESH:D003288), -bowel lesions (MESH:D015212), Arteriovenous malformations (MESH:D001165), weight loss (MESH:D015431), congestion (MESH:D002311), melena (MESH:D008551), anemia (MESH:D000740), portal hypertension (MESH:D006975)
- **Chemicals:** iron (MESH:D007501)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12937901/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12937901/full.md

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Source: https://tomesphere.com/paper/PMC12937901