# Development and Biomechanical Evaluation of a Modular Knee Prosthesis: From Conceptual V1 Design to an Improved V3 Model

**Authors:** Samal Abdreshova, Sayat Akhmejanov, Kassymbek Ozhikenov, Nursultan Zhetenbayev, Yerkebulan Nurgizat, Dauren Bizhanov, Aidos Sultan, Abu-Alim Ayazbay, Meruert Zharmagambetova, Gani Sergazin

PMC · DOI: 10.3390/bioengineering13020201 · Bioengineering · 2026-02-11

## TL;DR

This paper presents the development and testing of a modular knee prosthesis, improving motion and functionality across three design versions.

## Contribution

The novel contribution is a modular, cost-effective knee prosthesis with enhanced biomechanical performance and modularity.

## Key findings

- The V3 model achieved an extended range of motion and smoother dynamic response.
- The V3 design reduced mass and lowered the center of gravity compared to earlier versions.
- The final model is compatible with a fully modular foot–ankle–knee configuration.

## Abstract

This study investigates the functional capabilities and accessibility limitations of current knee prostheses while developing and evaluating a three-stage prosthetic system (V1–V3). The primary objective is to design a cost-effective knee prosthesis featuring anatomically compatible motion, high kinematic accuracy, and a modular architecture. The methodology integrates a technical review of commercial prostheses, CAD modeling in SolidWorks, kinematic evaluation through Motion Simulation, and experimental testing of the V2 prototype. The results demonstrate the structural limitations of the initial V1 design, the complete assembly and improved functional performance of the V2 prototype, and the advanced mechanical behavior achieved in the final V3 concept. The V3 model provides an extended range of motion, reduced mass and lowered center of gravity, smoother dynamic response, and compatibility with a fully modular foot–ankle–knee configuration. Overall, the findings indicate that the V3 design represents a promising engineering solution that brings the system closer to clinical applicability and establishes a foundation for the development of a fully modular lower-limb prosthetic platform.

## Full-text entities

- **Genes:** CLEC4D (C-type lectin domain family 4 member D) [NCBI Gene 338339] {aka CD368, CLEC-6, CLEC6, CLECSF8, Dectin-3, MCL}, PHF1 (PHD finger protein 1) [NCBI Gene 5252] {aka MTF2L2, PCL1, TDRD19C, hPHF1}
- **Diseases:** falls (MESH:C537863), fatigue (MESH:D005221), stroke (MESH:D020521), Knee joint amputation (MESH:D000092443), injury to (MESH:D014947), Femorotibial torsion (MESH:D050723), musculoskeletal complications (MESH:D009140), lateral deviation of the knee (MESH:D007718)
- **Chemicals:** PETG (MESH:C066907), carbon (MESH:D002244), polymer (MESH:D011108), PLA (MESH:C033616), polyurethane (MESH:D011140), Al6061-T6 (-), aluminum (MESH:D000535)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12937899/full.md

## Figures

15 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12937899/full.md

## References

45 references — full list in the complete paper: https://tomesphere.com/paper/PMC12937899/full.md

---
Source: https://tomesphere.com/paper/PMC12937899