# Advancing Scoliosis Treatment with Patient-Specific Functionally Graded NiTi-SMA Rods: Key Considerations and Development Objectives

## TL;DR

This paper proposes a new approach for scoliosis treatment using 3D-printed, patient-specific NiTi rods with tailored mechanical properties to improve correction and preserve motion.

## Contribution

The paper introduces a materials-to-clinic framework for functionally graded NiTi rods using additive manufacturing for scoliosis correction.

## Key findings

- Functionally graded NiTi rods can provide adaptive transformation temperature gradients and tunable mechanical responses.
- Additive manufacturing enables spatial programming of transformation temperatures and mechanical properties along the rod.
- A multi-objective optimization methodology links clinical classifications to design parameters for patient-specific rods.

## Abstract

This review develops a materials-to-clinic framework for patient-specific, functionally graded (FG) NiTi shape memory alloy (SMA) rods as a complementary paradigm for scoliosis correction that targets durable alignment with motion preservation. The article synthesizes the thermomechanical basis of NiTi (thermoelastic martensitic transformation, near constant superelastic plateau, and hysteretic damping) while leveraging additive manufacturing (AM) capabilities to spatially program transformation temperatures (e.g., Af), effective stiffness, and geometric inertia along the rod. Consolidated process–structure–property linkages are provided for the PBF-LB, DED, and BJAM routes, together with contamination and composition-control strategies (mitigation of Ni volatilization; management of O/C uptake; gradient heat treatments) and segment-level quality assurance (DSC mapping, micro-CT, EBSD/indentation, and bench bending/torsion in physiologic media). Building on clinical curve classification, the methodology formalizes a grading mask and target moment vector that drive multi-objective optimization of the segmental Af, relative density/architecture, and cross-section, followed by route-specific build plans and acceptance tolerances. A phenomenological constitutive description provides the forward map from local design variables to temperature-dependent moment–curvature loops for finite element verification and uncertainty control. Surgical handling and activation policies are codified (cold shaping in martensite and controlled intra-/postoperative warming within tissue-safe bounds), and a translational roadmap is outlined, encompassing prospective calibration of classification-to-design mappings, AM process maps with in situ monitoring, digital twin planning, and long-horizon fatigue/corrosion protocols. The proposed graded structures provide an adaptive transformation temperature gradient and tunable mechanical response, representing an important design direction toward 3D-printed, patient-specific SMA rods for durable, adjustable, and efficient scoliosis correction.