# Primary fungal iliopsoas abscess caused by Candida albicans: a rare clinical entity

**Authors:** Hazem Alouani, Ghazi Lâamiri, Manel Yaacoubi, Jasser Rchidi, Mahdi Bouassida, Hassen Touinsi

PMC · DOI: 10.1016/j.ijregi.2026.100850 · IJID Regions · 2026-01-29

## TL;DR

This paper reports a rare case of a fungal abscess in the iliopsoas muscle caused by Candida albicans in a diabetic patient, highlighting the importance of diagnosis and treatment.

## Contribution

The paper presents a rare clinical case of C. albicans causing iliopsoas abscess, emphasizing its diagnostic challenges and management.

## Key findings

- Candida albicans is an extremely rare cause of iliopsoas abscess.
- Diabetes increases the risk of fungal abscesses due to hematogenous spread.
- Combined drainage and antifungal therapy leads to favorable outcomes in such cases.

## Abstract

•Candida albicans is an extremely rare cause of iliopsoas abscess.•Diabetes predisposes to hematogenous fungal spread.•Fungal abscesses may initially mimic pyogenic infections.•Culture confirmation is essential, especially when empirical antibiotics fail.•Combined drainage and antifungal therapy lead to excellent outcomes.

Candida albicans is an extremely rare cause of iliopsoas abscess.

Diabetes predisposes to hematogenous fungal spread.

Fungal abscesses may initially mimic pyogenic infections.

Culture confirmation is essential, especially when empirical antibiotics fail.

Combined drainage and antifungal therapy lead to excellent outcomes.

Fungal iliopsoas abscesses are exceedingly rare and typically occur in immunocompromised individuals. Candida albicans is an uncommon pathogen in this location and may lead to delayed diagnosis due to its nonspecific clinical features. Groin extension of such abscesses is even more unusual.

We report a diabetic male patient with a large left iliopsoas abscess extending into the groin. Imaging showed a collection exceeding 10 cm. Initial empirical therapy included fluconazole. Combined surgical and percutaneous drainage was performed. Culture of the drained pus grew C. albicans, confirming a fungal iliopsoas abscess. The clinical outcome was favorable.

Fungal iliopsoas abscesses represent a rare subset of deep-seated fungal infections. Diabetes is an important predisposing factor. Diagnosis relies on imaging and microbiological confirmation. C. albicans is seldom isolated from iliopsoas collections, making this case noteworthy. Optimal management includes drainage and targeted antifungal therapy.

C. albicans iliopsoas abscesses are rare and should be suspected in diabetic or non-responding patients. Early identification and tailored antifungal therapy are essential for successful outcomes.

## Linked entities

- **Chemicals:** fluconazole (PubChem CID 3365)
- **Diseases:** diabetes (MONDO:0005015)
- **Species:** Candida albicans (taxon 5476)

## Full-text entities

- **Diseases:** leukocytosis (MESH:D007964), Iliopsoas abscess (MESH:D016659), infection (MESH:D007239), urinary symptoms (MESH:D059411), chills (MESH:D023341), gastrointestinal infection (MESH:D005767), Diabetes (MESH:D003920), , flank, and groin pain (MESH:D021501), Pain (MESH:D010146), inguinal swelling (MESH:D006552), back pain (MESH:D001416), inflammatory (MESH:D007249), abscess (MESH:D000038), trauma (MESH:D014947), invasive candidiasis (MESH:D058365), Infectious Diseases (MESH:D003141), Fungal (MESH:D009181), spinal disease (MESH:D013122), gastrointestinal or genitourinary disease (MESH:D000091642), ketoacidosis (MESH:D007662), fever (MESH:D005334), candidiasis (MESH:D002177), limitation of hip movement (MESH:D025981), odontogenic infection (MESH:D018126), tenderness (MESH:D063806), musculoskeletal disorders (MESH:D009140), bacterial (MESH:D001424)
- **Chemicals:** Sabouraud dextrose agar (-), Blood glucose (MESH:D001786), Fluconazole (MESH:D015725)
- **Species:** Candida [taxon 1535326], Homo sapiens (human, species) [taxon 9606], Staphylococcus aureus (species) [taxon 1280], Bacteria Latreille et al. 1825 (Bacteria stick insect, genus) [taxon 629395], Mycobacterium tuberculosis (species) [taxon 1773], Candida albicans (species) [taxon 5476], Human immunodeficiency virus 1 (no rank) [taxon 11676]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12937149/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12937149/full.md

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Source: https://tomesphere.com/paper/PMC12937149