# Metanephric adenofibroma of the left kidney in an adult patient

**Authors:** Austin Erickson, Audra Garrigan, Trushar Patel

PMC · DOI: 10.1016/j.eucr.2026.103385 · Urology Case Reports · 2026-02-19

## TL;DR

A 29-year-old woman with a rare benign kidney tumor called metanephric adenofibroma underwent successful robotic surgery with no further treatment needed.

## Contribution

This case highlights the rare occurrence of metanephric adenofibroma in an adult, expanding clinical awareness of its presentation and management.

## Key findings

- Metanephric adenofibroma was diagnosed in a 29-year-old female with a left renal mass.
- The patient underwent robotic partial nephrectomy with negative surgical margins and benign histopathology.
- The patient recovered well and does not require further acute follow-up.

## Abstract

Metanephric adenofibroma is a rare, benign renal neoplasm arising from the embryonic metanephric tissue, which would typically give rise to normal kidney parenchyma. Despite classical presentation in pediatric patients, we present a case of a 29-year-old female with 6 months of intermittent left upper quadrant pain found to have a 3.8cm left renal mass, partially extending into the collecting system of the superior pole. The patient underwent robotic partial nephrectomy, and histopathology confirmed a diagnosis of metanephric adenofibroma with negative surgical margins. The patient had an uneventful recovery, and requires no acute follow-up, given the benign nature of her diagnosis.

## Linked entities

- **Diseases:** metanephric adenofibroma (MONDO:0002396)

## Full-text entities

- **Genes:** WT1 (WT1 transcription factor) [NCBI Gene 7490] {aka AWT1, GUD, NPHS4, WAGR, WIT-2, WT-1}, KRT7 (keratin 7) [NCBI Gene 3855] {aka CK7, K2C7, K7, SCL}, B3GAT1 (beta-1,3-glucuronyltransferase 1) [NCBI Gene 27087] {aka CD57, GLCATP, GLCUATP, HNK1, LEU7, NK-1}, AMACR (alpha-methylacyl-CoA racemase) [NCBI Gene 23600] {aka AMACRD, CBAS4, P504S, RACE, RM}, MAF (MAF bZIP transcription factor) [NCBI Gene 4094] {aka AYGRP, CCA4, CTRCT21, c-MAF}, CD34 (CD34 molecule) [NCBI Gene 947], BRAF (B-Raf proto-oncogene, serine/threonine kinase) [NCBI Gene 673] {aka B-RAF1, B-raf, BRAF-1, BRAF1, NS7, RAFB1}
- **Diseases:** hematuria (MESH:D006417), left upper quadrant pain (MESH:D010146), blood loss (MESH:D016063), benign renal neoplasm (MESH:D009369), MA (MESH:D000236), polycythemia (MESH:D011086), left (MESH:D018487), renal masses (MESH:C536030), Metanephric adenofibroma (MESH:D000232), renal cancers (MESH:D007680), ischemia (MESH:D007511), hypertension (MESH:D006973), MST (MESH:D046152), dizziness (MESH:D004244), Wilms tumor (MESH:D009396), abdominal mass (MESH:D000007), papillary renal cell carcinoma (MESH:D002292), necrosis (MESH:D009336)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Mutations:** BRAFV600E

## Full text

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## Figures

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12937011/full.md

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Source: https://tomesphere.com/paper/PMC12937011