# Effectiveness of solution-focused brief therapy on cancer patients: a systematic review and meta-analysis

**Authors:** Luqiang Zhou, Xiaojuan Yuan, Yan Li, Siyue Li, Fang Guo, Caiping Song, Yu Chen, Xi Xiong

PMC · DOI: 10.3389/fpsyg.2026.1741088 · Frontiers in Psychology · 2026-02-12

## TL;DR

This study reviews and analyzes how solution-focused brief therapy helps cancer patients with anxiety, depression, fatigue, and quality of life.

## Contribution

A systematic review and meta-analysis of SFBT's effectiveness in cancer care, highlighting its potential and limitations.

## Key findings

- SFBT significantly reduced anxiety, depression, and cancer-related fatigue in patients.
- Quality of life improved with SFBT, but the evidence quality is low due to study limitations.
- More rigorous research is needed to confirm the effectiveness of SFBT in cancer care.

## Abstract

The aim of this study was to review and meta-analyze the effectiveness of a nursing intervention based on solution-focused brief therapy (SFBT) in improving anxiety, depression, cancer-related fatigue, and quality of life in cancer patients.

Conducting a systematic evaluation and meta-analysis following the PRISMA guidelines, we performed a thorough search across various databases including Cochrane, PubMed, CINAHL, PsycInfo, EMBASE, CNKI, Wanfang Database, and VIP Database. The search was conducted from the inception of each database up to February 2024. The overall effect size of the intervention was determined by calculating the standardized mean difference (SMD) and its 95% confidence interval. Statistical analyses were conducted using Review Manager (RevMan) 5.4.1.

13 studies meeting the selection criteria were included, encompassing a total of 1146 patients in the final analysis. 8 research examined the impact on anxiety, 10 on depression, 6 on cancer-related fatigue, and 5 on quality of life. The standardized mean difference for anxiety was –1.52 (CI: –2.20 ∼ –0.84, p < 0.0001), depression was –1.54 (CI: –2.09 ∼ –1.00, p < 0.00001), cancer-related fatigue was –2.19 (CI: –3.33 ∼ –1.05, p = 0.0002), and quality of life status was 2.18 (CI: 0.73 ∼ 3.62, p = 0.003). The overall certainty of the evidence was rated low due to limitations such as lack of allocation concealment, blinding, lack of clinical trial registration for the majority of studies, and high risk of bias in several areas.

SFBT may be effective in reducing anxiety, depression, cancer-related fatigue and improving quality of life in cancer patients. However, due to the limitations of the original study, including a high risk of bias and significant heterogeneity, although the research results are encouraging, the overall quality of existing evidence is low, so we cannot draw clear conclusions. More robust research designs are needed to accurately evaluate the effects of this treatment.

## Linked entities

- **Diseases:** cancer (MONDO:0004992)

## Full-text entities

- **Diseases:** cancer of the digestive system (MESH:D004067), Anxiety (MESH:D001007), SFBT (MESH:D016609), Lung cancer and (MESH:D008175), myeloma (MESH:D009101), CRF (MESH:D009369), pain (MESH:D010146), C (OMIM:211750), Thyroid cancer (MESH:D013964), deaths (MESH:D003643), Cervical cancer (MESH:D002583), Leukemia (MESH:D007938), Colorectal Cancer (MESH:D015179), anemia (MESH:D000740), Bladder cancer (MESH:D001749), concentration difficulties (MESH:C567712), thyroid (MESH:D013966), hematologic neoplasms (MESH:D019337), Fatigue (MESH:D005221), low (MESH:D009800), system (MESH:D015619), lymphoma (MESH:D008223), nausea (MESH:D009325), Breast Cancer (MESH:D001943), Depression (MESH:D003866)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12936997/full.md

## References

42 references — full list in the complete paper: https://tomesphere.com/paper/PMC12936997/full.md

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Source: https://tomesphere.com/paper/PMC12936997