# Automated deep learning detection of orthodontically induced external apical root resorption in maxillary incisors on panoramic radiographs

**Authors:** Samet Özden, Betül Kula, Mahmut Tankuş

PMC · DOI: 10.1186/s40510-026-00610-9 · Progress in Orthodontics · 2026-02-26

## TL;DR

This paper introduces a deep learning model to detect root resorption in orthodontic patients using panoramic radiographs, showing strong performance in classification.

## Contribution

A novel YOLOv12-based pose estimation model is proposed for detecting root resorption with superior accuracy compared to object detection approaches.

## Key findings

- The pose estimation model achieved a weighted F1-score of 0.88, significantly higher than the object detection model's 0.60.
- The model demonstrated high accuracy (0.93) and strong discriminative ability (ROC-AUC of 0.90–0.99) across resorption stages.
- Most misclassifications occurred between neighboring resorption grades, indicating fine-grained performance.

## Abstract

This study aimed to develop and compare two YOLOv12-based deep learning models—object detection and pose estimation—for the automatic classification of orthodontically induced external apical root resorption (OIEARR) using panoramic radiographs.

A total of 624 panoramic radiographs obtained from 312 patients aged 10–18 who underwent at least 12 months of fixed orthodontic treatment were retrospectively analyzed. Each maxillary central and lateral incisor was graded for OIEARR severity on a 4-point scale (Grade 0 to Grade 3) by two experienced orthodontists serving as the ground truth. Two YOLOv12-based models were trained: an object detection (OD) model for regional analysis and a pose estimation (PE) model for anatomical landmark localization. Both models were trained and validated on annotated panoramic images and evaluated using accuracy, precision, recall, specificity, F1-score, confusion matrix, and ROC-AUC.

The PE model outperformed the OD model across all evaluation metrics, demonstrating superior performance in detecting OIEARR. Specifically, the PE model achieved a weighted F1-score of 0.88, compared to 0.60 for the OD model. It also showed higher accuracy (0.93 vs. 0.78), precision (0.88 vs. 0.64), and recall (0.88 vs. 0.59), confirming its robustness in root resorption classification. Particularly in Grade 1 and Grade 2 resorption categories, the PE model demonstrated markedly superior classification performance (F1 = 0.85 and 0.88, respectively), while maintaining excellent detection in Grade 3 cases (F1 = 0.95). Confusion matrix analysis revealed that most misclassifications occurred between neighboring grades. ROC-AUC values for the PE model were consistently high (0.90–0.99), indicating strong discriminative ability across all resorption stages.

The YOLOv12x PE model offers a reliable and sensitive tool for detecting varying degrees of root resorption on panoramic radiographs. Its fine-grained anatomical localization capabilities provide an advantage for early diagnosis, making it a promising approach for clinical decision support in orthodontics.

## Full-text entities

- **Diseases:** periodontal bone loss (MESH:D016301), bone loss (MESH:D001847), caries (MESH:D003731), mandibular fracture (MESH:D008337), confusion (MESH:D003221), EARR (MESH:D012391), periodontal (MESH:D010518), apical periodontitis (MESH:D010485)
- **Chemicals:** TN (-)
- **Species:** Homo sapiens (human, species) [taxon 9606], Canis lupus familiaris (dog, subspecies) [taxon 9615]

## Full text

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## Figures

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## References

1 references — full list in the complete paper: https://tomesphere.com/paper/PMC12936252/full.md

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Source: https://tomesphere.com/paper/PMC12936252