# When controls are healthy: the difficulty of testing neuroprotection in low-injury models

**Authors:** Wilhelm Behringer, Benjamin Abella, Jasmin Arrich, Bernd Boettiger, Michael Holzer

PMC · DOI: 10.1186/s40635-026-00868-7 · Intensive Care Medicine Experimental · 2026-02-25

## Full-text entities

- **Genes:** NEFL (neurofilament light chain) [NCBI Gene 100521224] {aka NF-L}
- **Diseases:** cardiac arrest (MESH:D006323), hypothermia (MESH:D007035), brain injury (MESH:D001930), brain insult (MESH:D001927)
- **Species:** Sus scrofa (pig, species) [taxon 9823]

## Full text

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Source: https://tomesphere.com/paper/PMC12936237