# Prevalence of premenstrual syndrome, premenstrual dysphoric disorder, and dysmenorrhea in nursing students: a systematic review, meta-analysis, and evidence-based recommendations

**Authors:** Sabyasachi Maity, Bharathi S. Gadad, Hansapani Rodrigo, Seham Noorani, Aneesha Usman, Chloe Lark, Mona Attarpour, Ivy Mageto, Lucas Schwartz, Anna Maria Trachuk, Dena Yaareb, Fadi Huzien, Nikhilesh Anand, Narendra Nayak, Jaime E. Mendoza, Shreya Nauhria, Samal Nauhria

PMC · DOI: 10.3389/fgwh.2025.1701704 · Frontiers in Global Women's Health · 2026-02-12

## TL;DR

This study finds that many nursing students suffer from menstrual disorders, which affect their academic performance and wellbeing, and suggests that schools should provide better support.

## Contribution

The paper provides updated prevalence estimates and evidence-based recommendations for addressing menstrual disorders in nursing students.

## Key findings

- Pooled prevalence of PMS was 62%, PMDD 21%, and dysmenorrhea 72% among nursing students.
- Students reported academic and social impacts like absenteeism and reduced concentration.
- Coping strategies were mostly self-directed, with limited use of institutional support or interventions.

## Abstract

Menstrual disorders—including premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), and dysmenorrhea—are highly prevalent among women of reproductive age and are associated with impaired academic performance, psychological distress, and reduced social functioning. Nursing students are particularly vulnerable due to the combined demands of intensive academic schedules and clinical training, yet prevalence estimates and institutional responses remain inconsistent.

A systematic review and meta-analysis were conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD420251109363). PubMed, Scopus, Web of Science, CINAHL Ultimate, and APA PsycINFO were searched for studies published between 2016 and 2025. Eligible studies reported prevalence or impact of PMS, PMDD, or dysmenorrhea exclusively in nursing students. The Joanna Briggs Institute checklist for prevalence studies was used for quality appraisal. Random-effects meta-analysis was applied to calculate pooled prevalence estimates, and thematic synthesis was used to evaluate academic, social, and psychosocial impacts, coping strategies, and interventions.

Twenty studies involving 5,131 nursing students were included. The pooled prevalence was 62% for PMS, 21% for PMDD (including severe PMS), and 72% for dysmenorrhea, with substantial heterogeneity (I2 > 80%). Reported impacts included absenteeism, reduced concentration, diminished clinical performance, and impaired quality of life. Coping strategies were largely self-directed, including analgesics, rest, and dietary modifications, while few students accessed formal healthcare or institutional support. Only a limited number of studies evaluated structured interventions such as exercise, yoga, or nutritional supplementation.

Menstrual disorders are highly prevalent among nursing students and carry significant academic, social, and psychological consequences. Nursing education programs should integrate routine screening, structured wellness initiatives, and evidence-based interventions to improve student wellbeing, reduce academic disruption, and strengthen workforce preparedness.

https://www.crd.york.ac.uk/PROSPERO/view/CRD420251109363, PROSPERO CRD420251109363.

## Linked entities

- **Diseases:** premenstrual syndrome (MONDO:0004169), premenstrual dysphoric disorder (MONDO:1010182), dysmenorrhea (MONDO:1060205)

## Full-text entities

- **Diseases:** attentional difficulties (MESH:D001289), impaired (MESH:D060825), irritability (MESH:D001523), Menstruation Disturbances (MESH:D008599), dizziness (MESH:D004244), mental health disorders (OMIM:603663), anxiety (MESH:D001007), CL (MESH:D002971), Menstrual disturbances (MESH:D004412), burnout (MESH:D002055), impaired quality of life (MESH:D003643), PMDD (MESH:D065446), sleep disturbance (MESH:D012893), pain (MESH:D010146), substance misuse (MESH:D009293), ischemia (MESH:D007511), PMS (MESH:D011293), impaired concentration (MESH:C567712), Functional impairment (MESH:D003072), obesity (MESH:D009765), depressed mood (MESH:D003866), mood swings (MESH:D019964), nausea/vomiting (MESH:D020250), academic (MESH:D007859), fatigue (MESH:D005221)
- **Chemicals:** prostaglandin (MESH:D011453), omega-3 fatty acids (MESH:D015525), sertraline (MESH:D020280), paroxetine (MESH:D017374), vitamin D (MESH:D014807), curcumin (MESH:D003474), OCs (-), caffeine (MESH:D002110), alcohol (MESH:D000438), progesterone (MESH:D011374), vitamin B6 (MESH:D025101), calcium (MESH:D002118), magnesium (MESH:D008274), fluoxetine (MESH:D005473), allopregnanolone (MESH:D011280)
- **Species:** Echium amoenum (species) [taxon 701470], Homo sapiens (human, species) [taxon 9606], Melissa officinalis (common balm, species) [taxon 39338]

## Full text

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## Figures

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## References

60 references — full list in the complete paper: https://tomesphere.com/paper/PMC12935937/full.md

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Source: https://tomesphere.com/paper/PMC12935937