# Does maintaining apical patency reduce early postoperative pain after root canal treatment? A randomized controlled trial in asymptomatic vital single-rooted teeth

**Authors:** Ozan Arda Deger, Sehnaz Yilmaz, Kübra Gürler

PMC · DOI: 10.1007/s00784-026-06788-w · Clinical Oral Investigations · 2026-02-26

## TL;DR

A study found that maintaining apical patency during root canal treatment does not reduce early postoperative pain in asymptomatic single-rooted teeth.

## Contribution

This study provides evidence that apical patency does not significantly affect early postoperative pain in single-rooted teeth.

## Key findings

- Maintaining apical patency did not significantly reduce postoperative pain within 48 hours.
- Pain scores decreased significantly over time in both groups.
- Analgesic intake was low and similar between groups.

## Abstract

The aim of this randomized controlled clinical trial was to evaluate the effects of implementing apical patency (AP) on early postoperative pain in asymptomatic vital single-rooted teeth.

Seventy-two patients with asymptomatic, vital, single-rooted teeth were randomly assigned to either the patency group or the non-patency group. In the patency group, a #10 K-file was gently extended 1 mm beyond the working length at each instrument change to maintain AP, whereas in the non-patency group, instrumentation was confined within the working length. All treatments were completed at one visit by a single operator using the One Curve NiTi rotary system (25/0.06 or 35/0.04; MicroMega, Besançon, France) and standardized irrigation (2.5% NaOCl, 17% EDTA). Pain was recorded on a Numerical Rating Scale (NRS) at 0–6, 6–12, 12–24, 24–36, and 36–48 h. The data were analyzed using Mann–Whitney U, χ²/Fisher, Friedman, and Generalized Estimating Equations (GEE) tests (α = 0.05).

The groups did not differ significantly in age, gender, or jaw location (p > .05). The pain scores were similar at all time intervals (p > .05) and decreased significantly over time in both groups (p < .001). From 12 to 24 h onward, most patients reported minimal or no pain. Analgesic intake within 48 h was infrequent and comparable between groups (p > .05).

In asymptomatic vital single-rooted teeth, maintaining AP did not significantly affect postoperative pain within the first 48 h after single-visit root canal treatment. Therefore, routine use of AP solely to reduce early postoperative pain is not warranted in this patient group.

For asymptomatic vital single-rooted teeth, AP should not be performed with the expectation of reducing early postoperative pain; its use should be considered based on case-specific clinical considerations rather than pain control alone.

## Linked entities

- **Chemicals:** NaOCl (PubChem CID 23665760), EDTA (PubChem CID 6049)

## Full-text entities

- **Diseases:** Postoperative pain (MESH:D010149), inflammatory (MESH:D007249), Pain (MESH:D010146), necrotic pulp (MESH:D003790), Dental or orofacial pain (MESH:D005157), infected (MESH:D007239), AP (MESH:D004374), caries (MESH:D003731), necrotic (MESH:D009336), cyst (MESH:D003560), bacterial infection (MESH:D001424)
- **Chemicals:** EDTA (MESH:D004492), epinephrine (MESH:D004837), ibuprofen (MESH:D007052), AH Plus (MESH:C534916), diamond (MESH:D018130), silicone (MESH:D012828), articaine hydrochloride (MESH:D002355), water (MESH:D014867), epoxy (MESH:D004853), NaOCl (MESH:D012973), AP (-), NiTi (MESH:C040654)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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Source: https://tomesphere.com/paper/PMC12935705