Editorial Expression of Concern: Ets-1 mediates upregulation of Mcl-1 downstream of XBP-1 in human melanoma cells upon ER stress
L. Dong, C. C. Jiang, R. F. Thorne, A. Croft, F. Yang, H. Liu, C. E. de Bock, P. Hersey, X. D. Zhang
Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsEndoplasmic Reticulum Stress and Disease · Heat shock proteins research · Galectins and Cancer Biology
Editorial Expression of Concern to: Oncogene 10.1038/onc.2011.87, published online 21 March 2011
The Editors-in-Chief would like to alert the readers that concerns have been raised regarding some of the data presented in this article. Speficically:
- Fig. 2c Mel-CV and MM200 images appear highly similar;
- Fig. 5a IRE1α MM200 (lanes 4-6) and 6e Ets-1 Mel-KD blots appear highly similar.
The authors have been able to replicate the data, but due to the age of the article, the original data could not be recovered. Readers are therefore advised to interpret these results with caution.
C. E. de Bock agrees to this Editorial Expression of Concern. R. F. Thorne does not agree to this Editorial Expression of Concern. The other authors have not responded to any correspondence from the editor or publisher about this Editorial Expression of Concern.