# Affect-focused psychodynamic psychotherapy for mothers diagnosed with cancer – A feasibility study

**Authors:** Astrid Kuylenstierna, Maria Romare Strandh, Greta Melzi, Henrik Lindman, Ylva Hellstadius, Camilla Sköld, Lisa Ljungman, Anna Wikman

PMC · DOI: 10.1016/j.invent.2026.100916 · Internet Interventions · 2026-02-16

## TL;DR

A study shows that online therapy can help mothers with cancer reduce psychological distress and is worth further testing.

## Contribution

This is the first feasibility study of affect-focused psychodynamic therapy for cancer patients via videoconferencing.

## Key findings

- Online AFPT was rated 8.4/10 in helpfulness with complete retention and efficient recruitment.
- Significant reductions in depression and anxiety symptoms were maintained at 6-month follow-up.
- Most secondary outcomes, like parenting concerns and self-efficacy, improved significantly.

## Abstract

Parents with cancer face elevated psychological distress, often exacerbated by parenting responsibilities. Affect-Focused Psychodynamic Therapy (AFPT) has shown efficacy in improving emotion regulation, psychological well-being and self-compassion, but its feasibility and preliminary effect in this population remains unexplored.

The aim of this study was to evaluate the feasibility, acceptability, safety, and preliminary effects on symptoms of depression and anxiety, of AFPT delivered via videoconferencing for parents with cancer.

The intervention consisted of 10 sessions of AFPT, specifically affect phobia therapy. Qualitative data were collected through post-intervention interviews and analysed using inductive content analysis. Quantitative data were collected through self-report questionnaires at pre-intervention, post-intervention, and at 6-month follow-up measuring symptoms of depression and anxiety (primary outcome), parenting concerns, emotion regulation, self-efficacy, adaptive affective functioning, closeness in the family and self-rated health. Quantitative data were analysed using dependent-samples t-tests, with Cohen's d for effect sizes, and McNemar tests.

Fifteen mothers with cancer participated in the study. Results demonstrated efficient recruitment, acceptable study procedures, complete retention, and a relevant and beneficial intervention rated 8.4/10 in helpfulness. Moreover, findings showed significant reductions in symptoms of depression (Cohen's d = 1.29) and of anxiety (Cohen's d = 1.06) from pre- to post-intervention, maintained at 6-month follow-up, together with improvements in a majority of the secondary outcomes.

Videoconferencing AFPT appears feasible, acceptable, and safe to use for mothers with cancer, with promising preliminary effects in reducing psychological distress. These findings support further evaluation of the intervention to determine its efficacy in this population using a randomized controlled trial.

•Online-delivered AFPT is feasible, acceptable, and safe for mothers with cancer.•Results show promising preliminary effects in reducing psychological distress.•This feasibility study supports a randomized controlled trial evaluation.

Online-delivered AFPT is feasible, acceptable, and safe for mothers with cancer.

Results show promising preliminary effects in reducing psychological distress.

This feasibility study supports a randomized controlled trial evaluation.

## Linked entities

- **Diseases:** cancer (MONDO:0004992)

## Full-text entities

- **Diseases:** GAD-7 (MESH:C537955), affect phobia (MESH:D010698), breast cancer (MESH:D001943), Depression (MESH:D003866), death (MESH:D003643), major depression (MESH:D003865), psychological distress (MESH:D012128), Anxiety Disorder (MESH:D001008), affect (MESH:D019964), suicidal ideation (MESH:D001072), fatigue (MESH:D005221), irritable (MESH:D001523), Cancer (MESH:D009369), anxiety (MESH:D001007)
- **Chemicals:** AFPT (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12934217/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12934217/full.md

## References

66 references — full list in the complete paper: https://tomesphere.com/paper/PMC12934217/full.md

---
Source: https://tomesphere.com/paper/PMC12934217