# Live IVUS-guided wiring in percutaneous coronary intervention: a case report

**Authors:** Rithik Mohan Singh Sindhi, Divyesh Sharma, Jack Andrews

PMC · DOI: 10.1093/ehjcr/ytag111 · European Heart Journal. Case Reports · 2026-02-12

## TL;DR

A case report shows how live IVUS guidance helped successfully perform a complex heart procedure when standard methods failed.

## Contribution

Demonstrates the novel use of real-time IVUS to guide wiring in a challenging coronary bifurcation.

## Key findings

- RT-IVUS enabled successful wire redirection into the true lumen of a complex bifurcation lesion.
- The procedure resulted in optimal stent expansion and a successful 3-month follow-up outcome.
- RT-IVUS guidance allowed safe and efficient revascularization when standard techniques failed.

## Abstract

Wiring in bifurcation percutaneous coronary intervention can be limited by severe angulation, adverse plaque biasing, and ostial ambiguity. Real-time intravascular ultrasound (RT-IVUS) guidance can augment wire manipulation when standard techniques fail.

A 49-year-old man with exertional angina had a critical lesion left anterior descending (LAD)-2nd diagonal bifurcation lesion (Medina 1,1,0) with TIMI 2 flow. Standard wiring (acutely angled wires, dual lumen, and angled microcatheters) repeatedly biased into the diagonal. Under RT-IVUS, the wire was redirected into the true lumen of mid-LAD, enabling lesion crossing, pre-dilatation, and implantation of a 3.5 × 26 mm2 DES with post-dilatation. Final IVUS showed optimal expansion (MSA 9 mm2). The patient was discharged same day; at 3 months, he remained asymptomatic with a patent stent.

RT-IVUS can overcome wiring failure in complex bifurcations by providing live intravascular guidance augmenting wire passage into true lumen, supporting safe, efficient revascularization.

## Full-text entities

- **Diseases:** ostial stenosis (MESH:D003251), exertional angina (MESH:C564288), QT prolongation (MESH:D008133), bifurcation lesion (MESH:C537283), LAD (MESH:D000094629), nephropathy (MESH:D007674), ventricular arrhythmia (MESH:D001145), coronary artery disease (MESH:D003324), myocardial infarction (MESH:D009203), calcification (MESH:D002114), vessel injury (MESH:C536223), asthma (MESH:D001249), anginal symptoms (MESH:D012816), restenosis (MESH:D023903), chronic total occlusions (MESH:D001157)
- **Chemicals:** cholesterol (MESH:D002784), calcium (MESH:D002118), aspirin (MESH:D001241), Lipid (MESH:D008055), P2Y12 inhibitor (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12933685/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12933685/full.md

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Source: https://tomesphere.com/paper/PMC12933685