# Magnitude, Presentation, and Management of Pelvic Organ Prolapse at a Tertiary Referral Hospital in Southwestern Uganda: Retrospective Medical Records Review (2014–2018)

**Authors:** Musa Kayondo, Rogers Kajabwangu, Dan Kaye, Richard Migisha, Brenda Ainomugisha, Onesmus Byamukama, Kalyebara Paul Kato, Henry M Lugobe, Verena Geissbüehler

PMC · DOI: 10.7759/cureus.102295 · Cureus · 2026-01-26

## TL;DR

This study examines the prevalence and treatment of pelvic organ prolapse among women in southwestern Uganda, finding that it is a significant issue often requiring surgery.

## Contribution

The study provides insights into the management and outcomes of pelvic organ prolapse in a Ugandan hospital setting.

## Key findings

- Pelvic organ prolapse accounted for 31.2% of pelvic floor disorder cases, with a prevalence of 2.3%.
- Most patients presented with advanced disease (stage III or IV) and underwent surgical treatment.
- Early postoperative complications occurred in 7.1% of surgically treated patients, primarily vaginal cuff sepsis.

## Abstract

Purpose: This study sought to determine the burden, clinical characteristics, and management approaches of pelvic organ prolapse (POP) among women admitted to the gynecology unit at Mbarara Regional Referral Hospital (MRRH) in southwestern Uganda.

Methods: A retrospective review was conducted of medical records for women treated for pelvic floor disorders (PFDs) at the gynecology unit of MRRH between January 2014 and December 2018. The PFDs evaluated included POP, genitourinary fistulas, anosphincter injuries, and other forms of urinary incontinence. For women diagnosed with POP, additional information regarding the type, stage, treatment modality, and postoperative complications was extracted. Descriptive statistics were summarized using frequencies, and comparisons were made using the chi-square test, with statistical significance set at p < 0.05.

Results: During the study period, 9,109 women were admitted to the gynecology unit, of whom 674 (7.4%) were diagnosed with PFDs. POP accounted for 210 (31.2%) of these cases, yielding a POP prevalence of 2.3% (95% CI: 2.0-2.61%). Uterine prolapse was the predominant type, observed in 77.1% of cases. The majority of patients (86.2%) presented with advanced disease (stage III or IV), and most (94.2%) received surgical treatment. Early postoperative complications occurred in 7.1% (14/198) of surgically managed patients, with vaginal cuff sepsis being the most frequent complication (5.1%; 10/198).

Conclusion: POP represents a significant proportion of gynecological admissions at MRRH and is predominantly treated surgically with a low rate of early postoperative complications. Preventive strategies should be strengthened to reduce the occurrence of POP, and greater emphasis should be placed on promoting less invasive treatment options, including the use of pessaries.

## Linked entities

- **Diseases:** pelvic organ prolapse (MONDO:0000082)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** POP (MESH:D056887), anterior compartment prolapse (MESH:D000868), visceral injuries (MESH:D007418), bladder injury (MESH:D001745), stress urinary incontinence (MESH:D014550), rectocele (MESH:D020047), urge incontinence (MESH:D053202), bleeding (MESH:D006470), PFD (MESH:C537241), abdominal pain (MESH:D015746), ureteric injury (MESH:D014515), rectal injuries (MESH:D012002), bowel injury (MESH:D012778), anosphincter injuries (MESH:D014947), disease (MESH:D004194), sepsis (MESH:D018805), overflow incontinence (MESH:D014549), prolapse (MESH:D011391), genitourinary fistula (MESH:D000091642), fistulas (MESH:D005402), urinary tract injury (MESH:D014570), Uterine prolapse (MESH:D014596), postoperative (MESH:D019106), PFDs (MESH:D059952), Vaginal cuff (MESH:D014627), tenderness (MESH:D063806), gynecologic disorders (MESH:D005831), urinary and fecal incontinence (MESH:D005242), cuff (MESH:D000070636), compartment prolapse (MESH:D003161), enterocele (MESH:D006547), cuff infection (MESH:D007239), postoperative complication (MESH:D011183), cystocele (MESH:D052858), MRRH (MESH:D003428)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

47 references — full list in the complete paper: https://tomesphere.com/paper/PMC12933507/full.md

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Source: https://tomesphere.com/paper/PMC12933507