# Reductions in ventilator-associated events following implementation of a ventilator-associated pneumonia diagnostic stewardship intervention: A difference-in-difference study

**Authors:** Owen Albin, Zachary Garcia, Jonathan Troost, Andrew Weirauch, Krishna Rao, Kevin Thompson, Emily Stoneman, Keith Kaye

PMC · DOI: 10.1017/ice.2025.10376 · Infection Control and Hospital Epidemiology · 2025-12-17

## TL;DR

A new intervention reduced unnecessary testing for ventilator-associated pneumonia without harming patients.

## Contribution

A bundled diagnostic stewardship intervention safely reduced PVAP overdiagnosis in ICU patients.

## Key findings

- Respiratory culturing rates decreased after the intervention.
- There was a significant reduction in possible ventilator-associated pneumonia events.
- Patient safety was not compromised during the intervention.

## Abstract

In this post hoc analysis of a quasi-experimental pilot/feasibility trial, a bundled diagnostic stewardship intervention safely reduced respiratory culturing rates without increasing ventilator-associated events (VAEs). Using difference-in-differences methodology, we observed a significant reduction in possible ventilator-associated pneumonia (PVAP) events, suggesting the intervention may reduce pneumonia overdiagnosis without compromising patient safety.

## Full-text entities

- **Diseases:** pneumonia (MESH:D011014), PVAP (MESH:D053717)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12932924/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12932924/full.md

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Source: https://tomesphere.com/paper/PMC12932924