# Ultrasound-responsive microbubbles in refractory infection niches: multi-front targeting of microenvironmental tolerance and local delivery of toxicity-limited antibiotics

**Authors:** Maxwel Adriano Abegg

PMC · DOI: 10.3389/fcimb.2026.1756357 · Frontiers in Cellular and Infection Microbiology · 2026-02-11

## Full-text entities

- **Diseases:** Cancer (MESH:D009369), inflammation (MESH:D007249), pulmonary infection (MESH:D012141), biofilm disease (MESH:D004194), hypoxia (MESH:D000860), hypoxic (MESH:D002534), toxicity (MESH:D064420), infection (MESH:D007239), death (MESH:D003643), infectious disease (MESH:D003141), necrosis (MESH:D009336), septic (MESH:D001170), allergy (MESH:D004342), acidity (MESH:D011015)
- **Chemicals:** ciprofloxacin (MESH:D002939), SonoVue (MESH:C420843), polymer (MESH:D011108), chitosan (MESH:D048271), oxygen (MESH:D010100), EPS (MESH:C100219), PAbetaN (MESH:C419365), fusidic acid (MESH:D005672), carbapenem (MESH:D015780), vancomycin (MESH:D014640), quinolone (MESH:D015363), Definity (MESH:C042852), S100A8/A9 (-), pO2 (MESH:C093415), Lipid (MESH:D008055)
- **Species:** Pseudomonas aeruginosa (species) [taxon 287], Mus musculus (house mouse, species) [taxon 10090], Enterobacterales (order) [taxon 91347], Homo sapiens (human, species) [taxon 9606], Staphylococcus epidermidis (species) [taxon 1282], Staphylococcus aureus (species) [taxon 1280], Bacteriophage sp. (species) [taxon 38018], Acinetobacter baumannii (species) [taxon 470]

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## References

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Source: https://tomesphere.com/paper/PMC12932609