# Application of GHOST-CAP strategy combined with multimodal monitoring in the treatment of a patient with polytrauma complicated by severe traumatic brain injury: a case report

## TL;DR

A 39-year-old man with severe brain injury and multiple injuries was successfully treated using a new eight-dimensional protocol and real-time monitoring.

## Contribution

The paper introduces the clinical application of the GHOST-CAP protocol combined with real-time multimodal monitoring for ultra-severe TBI.

## Key findings

- The patient's condition improved progressively with the GHOST-CAP strategy and multimodal monitoring.
- The treatment approach demonstrated clinical feasibility in managing ultra-severe TBI with polytrauma.

## Abstract

We report a 39-years-old man who sustained polytrauma with ultra-severe traumatic brain injury (TBI) after a fall from height; for the ultra-severe TBI component we innovatively applied the GHOST-CAP eight-dimensional goal-directed protocol and dynamically adjusted therapeutic targets under real-time guidance from multimodal neurologic monitoring. Following comprehensive management the patient’s condition improved progressively, illustrating the clinical feasibility of applying the GHOST-CAP strategy in conjunction with real-time multimodal neurologic monitoring in a patient with polytrauma complicated by ultra-severe TBI.