# Vaginal Ulcers Secondary to Stage Iv Uterine Prolapse Treated With L‐PRF

## TL;DR

This case study shows that L-PRF treatment helped heal vaginal ulcers in a 93-year-old woman with severe uterine prolapse who couldn't undergo surgery.

## Contribution

Demonstrates L-PRF as a novel, non-surgical treatment for chronic uterine ulcers in advanced prolapse cases.

## Key findings

- L-PRF treatment led to healing of non-surgical uterine ulcers in a high-risk patient.
- L-PRF showed advantages over conventional dressings in efficacy and safety.
- The method was cost-effective and well-tolerated in a patient with multiple comorbidities.

## Abstract

Pelvic organs prolapse (POP) is usually used to describe the pelvic organs' descent into or through the vagina. The related common complications are bleeding, extrusion, vaginal discharge, pain, and constipation; only older women and those with comorbidities seem to be most prone to persist with their use. Surgery is preferred, instead, by younger active women with advanced prolapse symptoms. The uterus lowers and slides into the vagina. Treatment varies by stage and severity. The purpose of this article was to evaluate the efficacy of LPRP in the treatment ofuterine ulcers in an old 93 years' obese patient with UP stage IV non‐surgically treatable. Obese 93‐year‐old woman with medical history of left hip replacement, bilateral knee replacement COPD with chronic pulmonary heart disease, renal failure, chronic heart failure, one hospitalization for acute heart failure, suffering from umbilical hernia, hypertension, hyperuricemia, polyhydric arthrosis, has had a complete uterine prolapse (grade IV) for 5 years. The patient has multiple vaginal ulcers as a consequence of urinary and fecal incontinence fluid in continuous contact with the occasionally inflamed everted vaginal mucosa. The ulcer area was infiltrated with L‐PRF membranes and covered with PRF, which were sutured and protected with an inverted glove. The results of the present case report show the positive effect of L‐PRF on the uterine ulcers that is a promising treatment for vaginal ulcers in case of prolapse. In conclusion, L‐PRF has shown significant potential as an effective treatment for chronic non‐healing uterine ulcers, offering advantages over conventional dressings in terms of efficacy, safety, and cost‐effectiveness.

The purpose of this article was to evaluate the efficacy of LPRP in the treatment of vaginal ulcers in an old 93 years' obese patient with UP stage IV non‐surgically treatable. In conclusion, L‐PRF has shown significant potential as an effective treatment for chronic non‐healing uterine ulcers, offering advantages over conventional dressings in terms of efficacy, safety, and cost‐effectiveness.