# Neuroform Atlas stent-assisted coiling of wide-necked intracranial bifurcation aneurysms

**Authors:** Cheng Zhang, Yang Zhang, Chunwei Li, Shengli Shen, Hongzhou Duan

PMC · DOI: 10.3389/fneur.2026.1737361 · Frontiers in Neurology · 2026-02-11

## TL;DR

This study shows that using the Neuroform Atlas stent during coiling is a safe and effective way to treat complex brain aneurysms.

## Contribution

The study provides real-world evidence of the safety and efficacy of the Neuroform Atlas stent for treating wide-necked intracranial bifurcation aneurysms.

## Key findings

- Neuroform Atlas stent-assisted coiling achieved complete aneurysm occlusion in 85.2% of cases immediately after the procedure.
- At follow-up, 94.5% of treated aneurysms remained completely occluded with minimal complications.
- Most patients (98.6%) had favorable clinical outcomes with minimal disability after treatment.

## Abstract

To evaluate the safety and efficacy of Neuroform Atlas stent-assisted coiling in the endovascular treatment of wide-necked intracranial bifurcation aneurysms.

We retrospectively reviewed 76 patients with wide-necked intracranial bifurcation aneurysms who underwent Neuroform Atlas stent-assisted coiling at our institution between August 2021 and December 2024. Patient demographics, aneurysm characteristics, procedural details, and procedure-related complications were collected and analyzed. Angiographic and clinical outcomes were assessed both postoperatively and during follow-up. The modified Rankin Scale (mRS) was used to evaluate clinical outcomes, and Raymond-Roy occlusion classification (RROC) grades were used to determine the degree of aneurysm occlusion.

A total of 76 patients harboring 81 wide-necked intracranial bifurcation aneurysms were included in the study. Among them, 17 patients (22.4%) presented with subarachnoid hemorrhage (SAH) at admission. A total of 87 Neuroform Atlas stents were successfully deployed in all patients. Immediate post-procedural angiography demonstrated complete occlusion in 69 aneurysms (85.2%, Raymond–Roy class I) and residual neck in 12 aneurysms (14.8%, Raymond–Roy class II). Procedure-related complications occurred in 4 patients (5.3%), including intraprocedural aneurysm rupture in 2 patients (2.6%), coil migration in 1 patient (1.3%), and parent artery hemorrhage in 1 patient (1.3%). Clinical follow-up was available for 72 patients (94.7%) at 6–18 months (mean, 12 months). At the last follow-up, 68 patients (94.4%) had an mRS score of 0, 3 patients (4.2%) had a score of 2, and 1 patient (1.4%) had a score of 3. A favorable clinical outcome (mRS ≤ 2) was achieved in 71 patients (98.6%), whereas 1 patient (1.4%) had a poor outcome (mRS>2). Angiographic follow-up was performed in 68 patients (89.5%) with 73 treated aneurysms (90.1%) at 6–18 months (mean, 12 months) after embolization. Complete occlusion (Raymond-Roy class I) was observed in 69 aneurysms (94.5%), and residual neck (Raymond-Roy class II) was found in 4 aneurysms (5.5%).

Neuroform Atlas stent-assisted coiling is a feasible and effective endovascular treatment strategy for wide-necked intracranial bifurcation aneurysms. This technique is associated with high aneurysm occlusion rates, favorable clinical outcomes, and low procedure-related morbidity.

## Linked entities

- **Diseases:** subarachnoid hemorrhage (MONDO:0005099)

## Full-text entities

- **Diseases:** cardiac or pulmonary dysfunction (MESH:D006331), aneurysm rupture (MESH:D017542), stroke (MESH:D020521), -Roy occlusion (MESH:C535875), thromboembolic (MESH:D013923), hemorrhage (MESH:D006470), intracranial hemorrhage (MESH:D020300), bifurcation (MESH:C537283), gastrointestinal bleeding (MESH:D006471), parent artery injury (MESH:D063129), stenosis (MESH:D003251), CL (MESH:D002971), SAH (MESH:D013345), occlusion (MESH:D001157), hematologic disorders (MESH:D006402), thrombosis (MESH:D013927), Intracranial bifurcation aneurysms (MESH:D002532), anterior circulation aneurysms (MESH:D020520), ischemic stroke (MESH:D002544), HD (MESH:D006816), ischemic (MESH:D002545), aneurysm occlusion (MESH:D000783)
- **Chemicals:** AA (MESH:D016718), Tirofiban (MESH:D000077466), aspirin (MESH:D001241), ticagrelor (MESH:D000077486), Solitaire AB (-), clopidogrel (MESH:D000077144), ADP (MESH:D000244)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

33 references — full list in the complete paper: https://tomesphere.com/paper/PMC12932210/full.md

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Source: https://tomesphere.com/paper/PMC12932210