# Editorial: Challenges and opportunities in tumor metabolomics **Authors:** Lei Yin, Cheng Kong, Chunmiao Cai, Hongqi Teng, Zhengyan Chang PMC · DOI: 10.3389/fmolb.2026.1796372 · Frontiers in Molecular Biosciences · 2026-02-11 ## Full-text entities - **Genes:** GLUL (glutamate-ammonia ligase) [NCBI Gene 2752] {aka DEE116, GLNS, GS, PIG43, PIG59}, BRAF (B-Raf proto-oncogene, serine/threonine kinase) [NCBI Gene 673] {aka B-RAF1, B-raf, BRAF-1, BRAF1, NS7, RAFB1}, MAPK7 (mitogen-activated protein kinase 7) [NCBI Gene 5598] {aka BMK1, ERK4, ERK5, PRKM7}, LPCAT1 (lysophosphatidylcholine acyltransferase 1) [NCBI Gene 79888] {aka AGPAT10, AGPAT9, AYTL2, LPCAT-1, LPLAT8, PFAAP3}, MAP2K7 (mitogen-activated protein kinase kinase 7) [NCBI Gene 5609] {aka JNKK2, MAPKK7, MEK, MEK 7, MKK7, PRKMK7}, CMPK1 (cytidine/uridine monophosphate kinase 1) [NCBI Gene 51727] {aka CK, CMK, CMPK, UMK, UMP-CMPK, UMPK}, ERBB2 (erb-b2 receptor tyrosine kinase 2) [NCBI Gene 2064] {aka CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19}, MAP2K5 (mitogen-activated protein kinase kinase 5) [NCBI Gene 5607] {aka HsT17454, MAPKK5, MEK5, PRKMK5}, NFE2L2 (NFE2 like bZIP transcription factor 2) [NCBI Gene 4780] {aka IMDDHH, NRF2, Nrf-2}, CD8A (CD8 subunit alpha) [NCBI Gene 925] {aka CD8, CD8alpha, IMD116, Leu2, p32}, FGF17 (fibroblast growth factor 17) [NCBI Gene 8822] {aka FGF-13, FGF-17, HH20}, CD63 (CD63 molecule) [NCBI Gene 967] {aka AD1, HOP-26, ME491, MLA1, OMA81H, Pltgp40}, SOX2 (SRY-box transcription factor 2) [NCBI Gene 6657] {aka ANOP3, MCOPS3}, FGFR4 (fibroblast growth factor receptor 4) [NCBI Gene 2264] {aka CD334, JTK2, TKF} - **Diseases:** lung squamous cell carcinoma (MESH:D002294), non-small cell lung cancer (MESH:D002289), hypoxia (MESH:D000860), uveal melanoma (MESH:C536494), hypoxic (MESH:D002534), myocardial infarction (MESH:D009203), Tumor (MESH:D009369), bone tumors (MESH:D001859), urothelial carcinoma (MESH:D014523), osteosarcoma (MESH:D012516), inflammation (MESH:D007249), melanoma (MESH:D008545), intraocular malignancies (MESH:C563596), metastasis (MESH:D009362) - **Chemicals:** cholesterol (MESH:D002784), lipid (MESH:D008055), glutamine (MESH:D005973), lactate (MESH:D019344), cisplatin (MESH:D002945) - **Species:** Homo sapiens (human, species) [taxon 9606] ## Full text _Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12932166/full.md ## References 11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12932166/full.md --- Source: https://tomesphere.com/paper/PMC12932166